Regis NU641 Adv Clinical Pharmacology: Neurology Exam Questions and Answers

Urecholine - Answer- is an example of a cholinergic drug Neostigmine - Answer- used to treat myasthenia gravis Cholinergic agents - Answer- are organ specific Cholinesterase inhibitors - Answer- are used to treat Alzheimers's disease & myesthenia gravis Donepezil (Aricept) - Answer- used to treat mild to moderate dementia caused by Alzheimer's disease. improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical called acetylcholine. If my patient was on a dopaminergic agent, important labs to monitor would be - Answer- LFTs & renal function What is another name for a cholinergic agent? - Answer- parasympathomimetric myasthenia gravis (MG) - Answer- autoimmune neuromuscular disorder characterized by weakness of voluntary muscles that is not curable Donezepil may be chosen over other agents due to - Answer- longer duration of action and better side effect profile acetylcholine - Answer- Dopaminergic agents attempt to restore the balance of dopamine and this neurotransmitter dopamine - Answer- A major goal of Parkinson's is to restore this in the brain amantadine - Answer- A common agent for the treatment of Parkinson's N/V, Hallucinations, & confusion - Answer- Common side effects with dopaminergic are NSAIDs - Answer- Patient has an early onset migraine this agent should be tried first Anticonvulsants - Answer- are not used just to treat seizure disorders Antiseizure drugs - Answer- work by stimulating an influx of CL ions, delaying NA and CA ions gingival hyperplasia - Answer- Maybe an UNUSUAL side effect, s/t Phenytoin (Dilantin) being a hydantoin agent blood dyscrasias - Answer- black box warning for tegretol butalbital preparation - Answer- A midrange migraine treatment for a patient that is not responding to NSAIDs might be vasoconstriction and constipation - Answer- Ergot preparations such as cafergot work by causing this Zolpidem (Ambien) - Answer- Sedatives or hypnotics are often used for sleep. a common agent would be ADD/ADHD - Answer- Treatment consists of stimulants being used heavily Atomoxetine(Strattera) - Answer- non-amphetamine stimulant Tension - Answer- Neck stiffness is often associated with which type of headache classic migraine - Answer- A migraine with aura abort headache - Answer- Goals of migraine therapy Serotinin 5-HT antagonist or triptans - Answer- are a common migraine treatment CAD, Uncontrolled HTN - Answer- contraindication for a triptan such as sumatriptan antiemetic - Answer- It is common to give this with abortive migraine treatment beta blocker, tricyclic antidepressant, & antiepileptic - Answer- Tx for a patient that is having 3 migraines per month Metoprolol - Answer- beta blocker for my asthmatic patient with migraine serotonin - Answer- Amitriptyline work on these receptors tension headache - Answer- patient reports band like pressure of the head that may last for days Nonpharmacologic measures - Answer- should be used with muscle tension headaches indomethacin - Answer- patient with hemicrania continua will likely respond to beta blocker, tca, DHE + antiemetic, or fluoxetine - Answer- chronic daily headaches might respond to cluster headache - Answer- Unilateral, severe periorbital headache with tearing and conjunctival erythema, that does not last for days, and oxygen can be used for treatment sumatriptan, intranasal lidocaine, ergotamine derivatives - Answer- Potential drug therapy for cluster headaches midrin + cyproheptadine, naproxen - Answer- Analgesic detoxification for medication overuse headache may require