advanced pathophysiology NR 507 final exam with verifired correct Answers

advanced pathophysiology NR 507 final exam with verifired correct Answers What are the effects of TSH on the thyroid? - ANSWER-increase in release of stored thyroid hormone, increase in iodide uptake and oxidation, and increase in thyroid hormone synthesis, increase in the synthesis and secretion of prostaglandins by the thyroid. Thyroid hormones have a ____________feedback effect. - ANSWER-Negative Thyroid hormone inhibits what hormones? - ANSWER-TRH and TSH which decreased TH synthesis and secretion. T3 and T4 thyroid hormones regulate many functions in body. - ANSWER- Calcitonin - ANSWER-Elevated serum calcium (major stimulant for calcitonin), regulates gastrin, pregnancy, lowered serum calcium, (suppresses calcitonin release). Calcitonin lowers serum calcium by opposing bone resorbing effects of PTH, prostaglandins, and calciferols by inhibiting osteoplastic activity. Thyroid hormones affect many body tissues and influence the genetic expression of specific proteins. They affect cell metabolism by altering what? - ANSWER-protein, fat and glucose metabolism, and as a result heat production and oxygen consumption are increased. Calcitonin is used to treat what? - ANSWER-Osteoporosis, osteoarthritis, Paget bone disease, hypercalcemia, osteogensesis imperfecta, and metastatic cancer of bone. Precursor molecule to calcitonin is what? - ANSWER-procalcitonin (stress hormone) which is elevated in infection and inflammation and can aid in diagnosing disease. Parathyroid glands. - ANSWER-2 pairs but may range from 2-6. Located behind the upper pole and lower pole of the thryoid gland.