PACOP - Pharmaceutical Chemistry (Pink)| 600 Questions with 100% Correct Answers | Verified | 170 Pages

1. Which of the following is(are) true regarding phase I drug metabolism? I. Also known as conjugation reaction II. Includes oxidation, reduction, hydrolysis III. Generally tends to provide a functional group or "handle" to the molecule a. I, II and III b. I and II only c. I only d. II and III only e. I and III only - D 2. Which of the following is(are) true regarding phase II drug metabolism? I. Allows the attachment of small, polar, and ionisable endogenous compounds II. Allows the termination or attenuation of a biologic activity III. Serves to protect the body against chemically reactive compounds or metabolites a. I, II and III b. I and II only c. I only d. II and III only e. I and III only - A3. Which of the following undergo oxidative reaction? I. Olefins II. Alcohols and Aldehydes III. Aromatic moieties IV. Nitro and Azo compounds a. I, II and III only b. II, III and IV only c. III only d. I and II only