NAPLEX - Sickle Cell Disease questions with correct answers

10-20 days - Answer (Sickle Cell Disease) SCD arises from a genetic mutation where patients with homozygous inheritance have RBCs that code for *HgbS*, which hemolyze after _______ 2-3 months - Answer (Sickle Cell Disease) Symptoms of SCD develop about _____ after birth, since infants have RBCs that have fetal hemoglobin (HgbF) which can compensate Chronic Pain, Avascular Necrosis, Pulmonary HTN, Renal Impairment - Answer (Sickle Cell Disease) The most common chronic complications of SCD include (4) S pneumoniae, H influenzae, N meningitidis - Answer (Sickle Cell Disease) The spleen is responsible for immune defense against encapsulated organisms such as (3) - Functional asplenia in SCD increases risk for infections 10 - Answer (Sickle Cell Disease)