Exam (elaborations) NURS 660

Quetiapine (Seroquel) Serotonin-Dopamine Antagonist Atypical antipsychotic 3 MULTIPLE CHOICE OPTIONS How long does it take for quetiapine (Seroquel) to work Psychotic and manic symptoms can improve within one week. It will take several week to have full effect on behavior. Recommended to wait 4-6 weeks to determine efficacy. May take 16-20 weeks to show good response on cognitive symptoms What does quetiapine do? Decrease positive symptoms of schizophrenia 3 MULTIPLE CHOICE OPTIONS What should be monitored closely before patients are on atypical antipsychotics? BMI Waist circumference Blood glucose levels (fasting blood glucose between 100-125) How are side effects of quetiapine caused? Sedation (by blocking H1 receptors) Dizziness, sedation, hypotension (by blocking alpha 1 adrenergic receptors Dry mouth, constipation, sedation (by blocking muscarinic 1 receptors) Weight gain, increased incidence of diabetes, dislipidemia, (reason for cause unknown)