Beta Lactam Antibiotics – PCN questions with correct answers

Basic MOA of PCN correct answer inhibitor of cell wall synthesis Are PCN bacteriocidal or bacteriostatic? correct answer Bacteriocidal Name 2 members of the beta-lactam family of antibiotics correct answer 1. Penicillins 2. Cephalosporins Name the site of action of penicillinase (beta-lactamase) correct answer Between the C and N on the beta lactam ring Name the chief structural requirement for bioloical activity correct answer penicillin nucleus what causes a loss of antibacterial activity of penicillins correct answer metabolic transformation ofr alteration of the penicillin nucleus Thickness of gram negative and gram positive cell walls correct answer gram positive 50-100 molecules thick gram negative 1 - 2 molecules thick Bacterial cell wall composition correct answer PEPTIDOGLYCANS Why does bacterial cell walls provide rigid mechanical stability cor