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Summary Portage Learning BIOD 152 A&P 2 Lab 6 - Histology of Body Systems

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LOOKING AT THE LIVER UNDER THE MICROSCOPE  Liver is made up of a lot of cylinders called Hepatic lobules.  The hepatic lobules are made up of sheets of liver cells called Hepatocytes  There is a center vein that passes through the middle of the hepatic lobules that drain the blood from the microscopic structures and then eventually the liver itself.  The interior of the liver under the microscope- think of spreading open a book cover to cover o The whole represents the central vein o Each page of the book represents a sheet of the hepatocyte  In between each sheet of hepatocyte there are channels called Sinusoids. o Sinusoids are blood channels that lead away from the central vein in the hepatic lobules. o Sinusoids contain some phagocytic cells (can’t see under the microscope)  Kupffer Cells- work to clean the blood and remove any debris from the blood in the liver  Hepatic Lobule under the microscope at the lowest power: o The white dot in the center of the lobule is the central vein (will eventually drain into the hepatic vein) o Increasing the magnification:  The red-ish areas are the hepatocytes. The white lines in between the red areas are the sinusoids.

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