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NRNP 6560 Midterm Exam

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Rheumatoid arthritis: what, who connective tissue, first that of jionts them other soft tissues (renal, cardiovascular, pulm). TNF-alpha plays a big role - more women than men - unknown cause - Epstein Barr virus Rheumatoid arthritis: Findings and diagnostics Correct answer- - symmetric joint/ muscle pain, worse in the morning then gets better - weakness, fatigue - anorexia, weight loss - generalized malaise - swollen joints/ boggy feeling of joints with deformity of joints - warm, red skin on affected joints later: - pleural effusions and pulmonary nodules - inflammation of sclerea (scleritis) - pericarditis, myocarditis - splenomegaly (Felty's syndrome) - anemia (hypochromic, microcytic) with low ferritin - possibly: positive rheumatoid factor - XR: joint swelling, later cortical and space thinning - synovial fluid: yellow, thick with elevated WBC up to 100.000 Felty's syndrome

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NRNP 6560 Midterm exam

Surgery risk classes
Correct answer- Class 1: benefits outweigh risk, should
be done Class 2a: reasonable to perform
Class 2b: should be
considered Class 3: rarely
appropriate

General rules for surgery: testing
Correct answer- ECG before surgery only if coronary disease, except when low
risk surgery
Stress test not indicated before surgery
Do not do prophylactic coronary revascularization

Meds before surgery
Correct answer- - Diabetic agents: Use insulin therapy to maintain glycemic
goals(iii) Discontinue biguanides, alpha glucosidase inhibitors,
thiazolidinediones, sulfonylureas, and GLP-1 agonists
- Do not start aspirin before surgery
- Stop Warfarin 5 days before surgery. May be bridged with Lovenox.
- Do not stop statin before surgery
- Do not start beta-blocker on day of surgery, but may continue

Assessment of surgical risk
Correct answer- - Unstable cardiac condition (recent MI, active angina, active
HF, uncontrolled HTN, severe valvular disease), concern with CAD, CHF.
arrhythmia, CVD
- patient stable or unstable?
- urgency of the procedure (oncology will be time sensitive)
- risk of procedure
- nutritional status
- immune competence
- determine functional capacity (need to be more than 4 METS, more than 10
METs makes low risk)

Low risk surgeries
Correct answer-
catarcts breast biopsy
cystoscopy, vasectomy
laporascopic
procedures Plastic
surgery

,intermediate risk surgeries
Correct answer- Head/ neck surgery

,thyroidectomy
Intraperitonea
l Prostate
Laminectomy
Hip/ knee
Hysterectomy
cholecystectom
y nephrectomy
non majot intrathoracic

High risk surgeries
Correct answer- aortic/
cabg transplants
spinal reconstruction
peripheral vascular
surgery

Lee's revised cardiac risk
index Correct answer- 6
points:
High risk surgery
= 1 CAD = 1
CHF = 1
Cerebrovascular disease =
1 DM 1 on insulin = 1
Creat greater than 2 = 1

1 = low risk
2 = moderate risk
3 = high risk

SCIP pre-operative infection measures
Correct answer- - Prophylactic antibiotics should be received within 1 h prior
to surgical incision
- be selected for activity against the most probable antimicrobial contaminants
- be discontinued within 24 h after the surgery end-time

Postoperative infection reduction methods
Correct answer- - pre-op hair removal
(clippers)
- wash hands
- normothermia
- maintain euglycemia
- urinary catheters are to be removed within the first two postoperative days

, Osteoarthritis: what, incidence
Correct answer- Slow destruction of bones/ joint followed by production of
replacement collagen which causes inflammatory changes

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