Colorectal Cancer (All Correct)

How much does the risk of colorectal cancer increase if a first degree relative has had it? Correct Answer 2-3X higher! men and women are affected equally in colon cancer, but rectal carcinoma is more common in... Correct Answer men what 2 ethnicities tend to present with more advanced stages and are 50% more likely to have fatal disease? Correct Answer African Americans and Hispanic Americans what type of polyps do not usually progress to cancer? Correct Answer hyperplastic polyps most colorectal screening has focused in early detection of what 2 things? Correct Answer colorectal cancer and adenomatous polyps at what size do polyps increase to 10% chance of becoming malignant in 10 years? Correct Answer 1 cm what are the 2 most common and clinically significant intestinal neoplasms? Correct Answer adenomatous polyps and adenocarcinoma *epithelial tumors of the large intestine colorectal cancer (CRC) develops from colorectal adenomas in almost all cases except... Correct Answer in IBD! how are adenomatous polyps removed? This could prevent colorectal carcinoma. Correct Answer - electrocautery during colonoscopy or sigmoidoscopy what are the risk factors for Colorectal Cancer? Correct Answer 1. Older age 2. African American 3. Personal history of CRC or adenomatous polyps 4. Family history of colorectal cancer 5. IBD 6. Genetic syndromes - family history of inherited genetic disorders, particularly familial adenomatous polyposis 7. Tobacco and alcohol use Germline mutations in what gene cause familial adenomatous polyposis? Correct Answer APC! what does a functional APC promote degradation of to prevent cell proliferation? Correct Answer Beta-catenin