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Summary

Summary Benzodiazepines

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Uploaded on
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Benzodiazepines summary. Quick review for Exams.

Institution
Kerala University Of Health Science
Course
210








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Connected book

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KD Tripathi Essentials of Medical Pharmacology
  • 2018
  • 9789352704996
  • Unknown

Written for

Institution
Kerala University Of Health Science
Course
210
All documents for this subject (1)

Document information

Summarized whole book?
No
Which chapters are summarized?
Chapter 29 : sedative-hypnotics
Uploaded on
February 26, 2023
Number of pages
2
Written in
2022/2023
Type
Summary

Subjects

  • benzodiazepines
  • bzd
  • sedative
  • hypnotic
  • pharmacology

Content preview

Benzodiazepines- Summary

Mechanism: Bind to GABAA channel & increase
frequency of channel opening & increase chloride ion
conductance and cause CNS depression(GABA
facilitatory)- do not open channel directly.
Site – Midbrain, ARAS and limbic system.
Prototype drug- Diazepam
Long Acting – Nitrazepam, Diazepam, Lorazepam
Short acting – Alprazolam, Triazolam


Actions-
CNS – Sedation, anterograde amnesia, anxiolytic,
muscle relaxant, anticonvulsant
Also reduce nocturnal gastric acid secretion
Uses
1. Insomnia
2. Anxiety
3. Epilepsy – status epilepticus & febrile seizures
4. Preanaesthetic medication
5. Muscle Relaxant
6. Alcohol withdrawal
7. IV Anaesthesia ( Midazolam)
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