ENDOCRINE RESPONSES TO
RESISTANCE EXERCISE
Chapter 4
, Page |1
Contents
Info........................................................................................................................................................................................ 2
Synthesis, Storage and Secretion of Hormones.....................................................................................................................5
Muscle as the Target for Hormonal Interactions...................................................................................................................6
Role of Receptors in Mediating Hormonal Changes..............................................................................................................7
Categories of Hormones........................................................................................................................................................9
Steroid hormone Interactions...........................................................................................................................................9
Polypeptide Hormone Interactions.................................................................................................................................10
Amine Hormone Interactions..........................................................................................................................................10
Heavy Resistance Exercise and Hormonal Increases...........................................................................................................11
Mechanisms of Hormonal Interactions...............................................................................................................................12
Hormonal Changes in Peripheral Blood...............................................................................................................................13
Adaptions in the Endocrine System.....................................................................................................................................14
Primary Anabolic Hormones................................................................................................................................................15
Testosterone................................................................................................................................................................... 15
Free Testosterone and Sex Hormone-Binding Globulin...............................................................................................16
Testosterone Responses in Women............................................................................................................................17
Training Adaptions of Testosterone............................................................................................................................19
Growth Hormone............................................................................................................................................................20
Growth Hormone Cont’d.................................................................................................................................................21
Growth Hormone Responses to stress........................................................................................................................22
Growth Hormone Responses in Women.....................................................................................................................22
Training Adaptions of Growth Hormone.....................................................................................................................22
Insulin-Like Growth Factors.............................................................................................................................................23
Exercise Responses of Insulin-Like Growth Factors.....................................................................................................24
Training Adaptions of Insulin-Like Growth Factor.......................................................................................................24
Adrenal Hormones..............................................................................................................................................................25
Cortisol............................................................................................................................................................................ 25
Role of Cortisol............................................................................................................................................................25
Resistance Exercise Response of Cortisol....................................................................................................................26
Catecholamines...............................................................................................................................................................27
Role of Catecholamines...............................................................................................................................................27
Training Adaptions of Catecholamines........................................................................................................................27
Other Hormonal considerations..........................................................................................................................................28
, Page |2
Info
Endocrine system supports the normal homeostatic function of the body and helps it respond to external stimuli
Part of complex signaling system in the human body to reflect changes and support exercise demands and
recovery
Importance= reflected by critical role played in theoretical development of periodization and training
General Adaption System (GAS)
1. Initial alarm reaction: reduction of function followed by increase in resistance to stress above previous
baseline
2. Adaption: increase in resistance to stress
o Key to continued beneficial adaption to stress is the timely removal of the stimulus so that function can
recover, and then reapplication of an often-increased stress (progressive overload)
Hormone signals= variety of roles from anabolic to permissive and catabolic
RESISTANCE EXERCISE
Chapter 4
, Page |1
Contents
Info........................................................................................................................................................................................ 2
Synthesis, Storage and Secretion of Hormones.....................................................................................................................5
Muscle as the Target for Hormonal Interactions...................................................................................................................6
Role of Receptors in Mediating Hormonal Changes..............................................................................................................7
Categories of Hormones........................................................................................................................................................9
Steroid hormone Interactions...........................................................................................................................................9
Polypeptide Hormone Interactions.................................................................................................................................10
Amine Hormone Interactions..........................................................................................................................................10
Heavy Resistance Exercise and Hormonal Increases...........................................................................................................11
Mechanisms of Hormonal Interactions...............................................................................................................................12
Hormonal Changes in Peripheral Blood...............................................................................................................................13
Adaptions in the Endocrine System.....................................................................................................................................14
Primary Anabolic Hormones................................................................................................................................................15
Testosterone................................................................................................................................................................... 15
Free Testosterone and Sex Hormone-Binding Globulin...............................................................................................16
Testosterone Responses in Women............................................................................................................................17
Training Adaptions of Testosterone............................................................................................................................19
Growth Hormone............................................................................................................................................................20
Growth Hormone Cont’d.................................................................................................................................................21
Growth Hormone Responses to stress........................................................................................................................22
Growth Hormone Responses in Women.....................................................................................................................22
Training Adaptions of Growth Hormone.....................................................................................................................22
Insulin-Like Growth Factors.............................................................................................................................................23
Exercise Responses of Insulin-Like Growth Factors.....................................................................................................24
Training Adaptions of Insulin-Like Growth Factor.......................................................................................................24
Adrenal Hormones..............................................................................................................................................................25
Cortisol............................................................................................................................................................................ 25
Role of Cortisol............................................................................................................................................................25
Resistance Exercise Response of Cortisol....................................................................................................................26
Catecholamines...............................................................................................................................................................27
Role of Catecholamines...............................................................................................................................................27
Training Adaptions of Catecholamines........................................................................................................................27
Other Hormonal considerations..........................................................................................................................................28
, Page |2
Info
Endocrine system supports the normal homeostatic function of the body and helps it respond to external stimuli
Part of complex signaling system in the human body to reflect changes and support exercise demands and
recovery
Importance= reflected by critical role played in theoretical development of periodization and training
General Adaption System (GAS)
1. Initial alarm reaction: reduction of function followed by increase in resistance to stress above previous
baseline
2. Adaption: increase in resistance to stress
o Key to continued beneficial adaption to stress is the timely removal of the stimulus so that function can
recover, and then reapplication of an often-increased stress (progressive overload)
Hormone signals= variety of roles from anabolic to permissive and catabolic
