LEHNINGER BIOCHEMISTRY CHAPTER 4 QUESTIONS WITH CORRECT ANSWERS

All of the following are considered "weak" interactions in proteins, except: A) hydrogen bonds. B) hydrophobic interactions. C) ionic bonds. D) peptide bonds. E) van der Waals forces. CORRECT ANSWER D) peptide bonds. The most important contribution to the stability of a protein's conformation appears to be the: A) entropy increase from the decrease in ordered water molecules forming a solvent shell around it. B) maximum entropy increase from ionic interactions between the ionized amino acids in a protein. C) sum of free energies of formation of many weak interactions among the hundreds of amino acids in a protein. D) sum of free energies of formation of many weak interactions between its polar amino acids and surrounding water. E) stabilizing effect of hydrogen bonding between the carbonyl group of one peptide bond and the amino group of another. CORRECT ANSWER A) entropy increase from the decrease in ordered water molecules forming a solvent shell around it. In an aqueous solution, protein conformation is determined by two major factors. One is the formation of the maximum number of hydrogen bonds. The other is the: A) formation of the maximum number of hydrophilic interactions. B) maximization of ionic interactions. C) minimization of entropy by the formation of a water solvent shell around the protein. D) placement of hydrophobic amino acid residues within the interior of the protein