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Maryville Pharm 615 Exam 3 Test, latest Top solution 2023

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Maryville Pharm 615 Exam 3 Test, latest Top solution 2023 Colchicine use - Reduce incidence of acute gout attacks relieves pain and discomfort (although it is not an analgesic) Colchicine Actions - inhibits migration of granulocytes to the inflamed areas Reduces lactic acid production by granulocytes decreases deposition of uric acid interferes with kinin formation and reduces phagocytosis Overall effect is it decreases the inflammatory response to urate crystals Colchicine cautions - Renal Failure- not effective in the presence of renal failure. Poorly excreted with RF. Hepatic dysfunction- associated with hepatotoxicity

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