Pathophysiology Practice Questions and answers, rated A, 2022 latest updates

Pathophysiology Practice Questions and answers, rated A, 2022 latest updates Document Content and Description Below Pathophysiology Practice Questions and answers, rated A, 2022 latest updates A patient has been diagnosed with acute lymphocytic leukemia (ALL) and asks the healthcare professional to describe it . What description by the professional is most accurate? a. ALL is a progressive neoplasm defined by the presence of greater than 30% lymphoblasts in the bone marrow or blood b. In ALL, immature blasts cells replace normal myelocytic cells, megakaryocytes, and erythrocytes c. B cells fail to mature into plasma cells that synthesize immunoglobulins d. The translocation of genetic material from genes 9 and 22 create an abnormal, fused gene identified as BCR-ABL - a. ALL is a progressive neoplasm defined by the presence of greater than 30% lymphoblasts in the bone marrow or blood Which of the following describes CML (Chronic Myelogenous Leukemia)? (Select all that apply.) a. Progresses rapidly b. Splenomegaly is a common finding in the accelerated phase c. Reciprocal translocation between chromosomes 9 and 22 (Philadelphia Chromosome) is present in 95% of cases d. Can lead to pancytopenia - b. Splenomegaly is a common finding in the accelerated phase c. Reciprocal translocation between chromosomes 9 and 22 (Philadelphia Chromosome) is present in 95% of cases d. Can lead to pancytopenia Folate and vitamin B12 deficiencies alter the synthesis of which of the following, which results in apoptotic destruction of maturing erythrocytes? a. Complement receptors on the cell surface b. Antigens on the cell surface c. DNA d. Mitochondria - c. DNA Hemophilia, a genetic bleeding disorder, is due to: a. Deficiencies of coagulation factor VIII, factor IX or factor XI b. Deficiency of tissue factor c. Deficiency in Vitamin K d. Deficiency of coagulation factor X - a. Deficiencies of coagulation factor VIII, factor IX or factor XI The characteristic sickling shape of the red blood cell in sickle cell anemia is due to: a. An autosomal recessive disease that results in the replacement of a proline amino acid with a threonine amino acid in hemoglobin β-chain b. An autosomal dominant disease that results in overproduction of RBCs c. Viral induced production of autoantibodies to hemoglobin resulting in RBC destruction d. A genetic point mutation resulting in the formation of abnormal hemoglobin (HbS) that is prone to stiffening - d. A genetic point mutation resulting in the formation of abnormal hemoglobin (HbS) that is prone to stiffening Which statement is true regarding fibromyalgia: a. It is characterized by limited area, localized joint and muscle pain b. Likely has no link to epigenetic alterations c. Likely is linked to neuroendocrine and stress-response alterations d. Rarely co-exists with other syndromes - c. Likely is linked to neuroendocrine and stress-response alterations Causes of Disuse Atrophy include: (Select all that apply): a. Aging b. Prolonged immobilization c. Nerve damage affecting limb function d. Space flight - a. Aging b. Prolonged immobilization c. Nerve damage affecting limb function d. Space flight Bone cells that resorb bone through action of digestive enzymes and cytokines are: a. Osteoblasts b. Osteocytes c. Osteoclasts d. Osteomyelites - c. Osteoclasts A compound fracture is characterized by: a. A fracture in two or more places b. A fracture that encircles the bone c. A fracture that also has a break in the skin d. Several fractures in the same bone that run parallel to the axis of the bone - c. A fracture that also has a break in the skin A nurse is caring for four patients in the cardiac unit with the following diagnoses. In which patient does the nurse assess for pulmonary emboli (PE) as a priority? a. Deep venous thrombosis b. Endocarditis c. Valvular disease d. Left heart failure - a. Deep venous thrombosis What effect does atherosclerosis have on the development of an aneurysm? a. Atherosclerosis causes ischemia of the intima. b. It increases nitric oxide. c. Atherosclerosis erodes the vessel wall. d. It obstructs the vessel. - c. Atherosclerosis erodes the vessel wall. Which elevated value may be protective against the develo