ATI Pharmacology Review with Complete Solutions-Good One!!

ATI Pharmacology Review with Complete Solutions-Good One!! Cephalosporin -broad spectrum -ceph/cefs -Similar to PCN/ don't give if PCN allergy -can cause bleeding w/ other bleeding meds monitor bleeding time (tonsil story) - Disulfiram reaction (puke & puke & puke) just like Flagyl, the protozoal drug - Store in fridge & take with food ALL antibiotics have these side effects - allergy, hypersensitivity - suprainfection - organ (kidney & ear) toxicity - lowers OC effectiveness Vancomyocin - serious infections like MRSA - colitis by c-diff - ototoxicity: get hearing test, tell dr. if hearing getting worse -given over 60 minutes Tetracyclines - Sumycin, Doxycycline (Vibramycin) - broad, rocky mtn fever, lyme disease, acne, GI infections by H. Pylori - bad GI discomfort - Don't give to kids ≤8; teeth permanently yellow - Bad photosensitivity- wear sunscreen! - Can't take with milk, iron, or antacids - Take on empty stomach with a full glass of water When is Arythromycin given? What class of drugs is it? worse adverse effect? When pt allergic to PCN and needs abx. Bacteriostatic inhibitor bad GI issues Aminoglycosides ototoxicity, Renal toxicity, Can't take with PCN at all! - gentamicin, neomycin, streptomycin TMP-SMZ -Contains Sulfa - use for UTI - Blood problems; get CBC baseline -photosensitivity wear sunscreen and glasses! - empty stomach with a full glass of water Isoniazid (INH) -antiTB - take daily for 6-12 months and most likely with other meds too -worked if 3 neg. sputum cultures, no temp. - Liver toxicity (hepato) check liver fxn - Don't take with alcohol (liver fxn remember?) - Take on empty stomach Antiviral: Acyclovir, Ganciclovir Teratogenic preg. X; put on rubber gloves if topical! remember my purple glove experience -thrombocytopenia, lowers WBC What class of drugs if Flagyl? What is the weird effect it has? protozoal. works on C. diff & H. Pylori PUD. Antibuse effect if taken with alcohol Amphotericin B anti-fungal. HIGHLY TOXIC - infusin rxns (fever and chills) - nephrotoxicity - hypokalemia - hepatoxicity - gynecomasita - C/I with aminoglycosides (just like PCN) -azole Fungal ______ causes malignant hyperthermia. Use ____ to stop it succinylcholine, Dantrium/Dantrolene. Morphine adverse effects -Constipation -Resp depression -urinary retention -Sedation - Orthostatic HOTN - Cough suppression Morphine drug-drug interactions (think of what morphine does to the body) - MAOIs -anticholinergics -CNS depressants -hypotensive drugs -opiod antagonists (narcan) - antihistamines Morphine patient education re how to take Take with food for N/V, lie still will help Opiod withdrawl (stop abruptly is taking ≥6weeks). Is