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THROMBOSIS essential note for BPT Essential Pathology for Physiotherapy Students,

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, Circulatory Disturbances Of Obstructive Nature
Thrombosis
Process of formation of solid mass in circulation from
constituents of flowing blood; the mass itself is called a thrombus
Blood clot is the mass of coagulated blood formed in vitro e.g. in a
tube
Haematoma is the extravascular accumulation of blood clot e.g. into
tissues.
Haemostatic plugs are the blood clots formed in healthy individual
the site of bleeding e.g. in injury to the blood vessel. Haemostatic pl
are useful as they stop the escape of blood and plasma

, Thrombosis
Thrombi developing in the unruptured cardiovascular system may
life-threatening by causing one of the following harmful effects:
1. Ischaemic injury - Thrombi may decrease or stop the blood suppl
part of an organ or tissue and cause ischaemia which may subseque
result in infarction
2. Thromboembolism - The thrombus or its part may get dislodged
be carried along in the bloodstream as embolus to lodge in a dis
vessel

, Pathophysiology
• Normally, there is an inbuilt system by which the blood remain
fluid state normally and guards against the hazards of thrombosis
haemorrhage
• Injury to the blood vessel initiates haemostatic repair mechanism or
thrombogenesis
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