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TBL COVID-19

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TBL COVID-19

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Uploaded on
October 13, 2022
Number of pages
3
Written in
2021/2022
Type
Other
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TBL COVID-19
Sars CoV 2 = RNA virus met spike eiwitten, bindt aan ACE 2

Bestrijding bestaat uit 3 punten
1. Expositie (testen testen!)
2. Profylaxe (vaccin)
3. Behandeling

Casus 1
56 jarige man bekend met obesitas en DM2 met dyspneu. U vermoedt infectie Sars
COV-2, opname indicatie. Wat stelt u voor?
- Diagnostiek? —> vitale parameters PCR, X thorax, CT, sneltesten andere virussen
(influenza), lab:
- CRP,
- D-dimeer,
- nier en lever functie, (ASAT hoog)
- Hb,
- Leuko’s,
- Lymfo’s (laag)
- ery’s
- Glucose
- LDH (hoog)
- CPK (hoog)
- Isolatie? —> JA! zo goed als mogelijk, sluis? Contact en druppel minimaal. Cohort
verpleging: verdacht en bewezen cohort.
- Behandeling? Antibiotica? Ontstekingsremmende medicatie? Antistolling?
- Antibiotica niet zinvol virus, maar superinfectie? Ceftriaxon
- Cortico’s. Aciclovir, remdesivir ??
- Antistolling want bedlederig
- Ondersteuning —> zuurstof, vocht

CO-RADS 1-5: 1 is geen afwijkingen, 5 is definitief covid (ook nog 6, positieve PCR).

Casus 2
Man 66 jaar, vg/ CVA en hypertensie. Milde griep, maar dagen later positieve PCR en
dan 3 dagen later opgenomen. Opvallend weinig dyspneu maar sat 88%, af 24, temp
38,5, longen bdz crepiteren.

Risicofactoren:
Leeftijd! Zelfs 50-59 al, neemt sterk toe.

3 fases van ziektebeloop
1; griepachtig, virus
2; respons host, cytokine storm (7-10 dagen na infectie)
3; je knapt niet op van ondersteunende behandeling —> ARDS, ICU

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