1.
2.
3.
4.Decreases elimination
Increase toxicity of Amio
CYP2D6
Alpha 1 Antagonist
CYP3A4
CYP2C9
Approved for: Focal, Generalized tonic-clonic, juvenile myoclonic epilepsy
Do not stop suddenly
Side effects:Somnolence, dizziness, anxiety, psychiatric manifestations
Serotonergic anxiolytics
Cholinesterase inhibitors
Levetiracetam (Keppra)
Beta 1 Antagonist
Effects heart muscle, blocks receptors in SA node to decrease hr, decrease contractility
Reduces bp, reduces arrethymias, decreases angina incidences
Metoprolol
Dopaminergics
Muscarinic Agonists
Beta 1 Antagonist
Cholinergic blockers
drugs used to control mood swings in patients with bipolar mood disorders
1 of 19 3/11/2021, 3:30 PMNR 565 Pharm Midterm |
NR 565 Pharm Midterm | 5.
6.
7.mood stabilizers
Schedule II
Preclinical research
Succinimides
block reuptake of serotonin and norepinephrine
treat depression, anxiety, enuresis in children, ocd, eating disorders
do not give to people with cardiac disease, causes sedation and anticholinergic effects
Amitriptyline, nortriptyline, imipramine, desipramine, clomipramine, doxepin, amoxapine.
Drugs that affect GABA
Centrally acting muscle relaxants
tricyclic antidepressants
atypical antipsychotics
Block the reuptake of NE and 5HT, treats depression, one kind treats fibrmyalgia
SE: increased bp, insomnia
do not stop suddenly
effexor, cymbalta, pristiq
tricyclic antidepressants
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
Norepinephrine and Serotonin Specific Agonists
Serotonin Agonist Reuptake Inhibitor
Treat glaucoma, improve GI/urinary bladder tone
Acetylcholine, Pilocarpine, Methacholine, Bethanechol
Cholinergic blockers
Muscarinic Agonists
2 of 19 3/11/2021, 3:30 PM 8.
9.
10.
11.Adrenergic agonists
Drugs that affect GABA
Decrease warfarin dose
Test for gene VCORC1 mutation
CYP2C9
alpha 2 agonists
NSAIDS
Aspirin
medication that exerts analgesic and anti-inflammatory actions
Treats fever, pain, rheumatoid arthritis, osteoarthritis, gout, dysmenorrhea, tendinitis
Anorexiants
Aspirin
NSAIDS
Lithium
Not always necessary to have a prescription
Loperamide, diphenoxylate and cough medicine with less than 200mg/100 ml pregabalin
Cholinergic blockers
Schedule V
Dopaminergics
Anorexiants
Treat parkinsons by enhancing dopamine
do not give to schizophrenic patients
levodopa (sinemet)
stand up slowly, inhibited by protein
Beta 1 Antagonist
3 of 19 3/11/2021, 3:30 PM
2.
3.
4.Decreases elimination
Increase toxicity of Amio
CYP2D6
Alpha 1 Antagonist
CYP3A4
CYP2C9
Approved for: Focal, Generalized tonic-clonic, juvenile myoclonic epilepsy
Do not stop suddenly
Side effects:Somnolence, dizziness, anxiety, psychiatric manifestations
Serotonergic anxiolytics
Cholinesterase inhibitors
Levetiracetam (Keppra)
Beta 1 Antagonist
Effects heart muscle, blocks receptors in SA node to decrease hr, decrease contractility
Reduces bp, reduces arrethymias, decreases angina incidences
Metoprolol
Dopaminergics
Muscarinic Agonists
Beta 1 Antagonist
Cholinergic blockers
drugs used to control mood swings in patients with bipolar mood disorders
1 of 19 3/11/2021, 3:30 PMNR 565 Pharm Midterm |
NR 565 Pharm Midterm | 5.
6.
7.mood stabilizers
Schedule II
Preclinical research
Succinimides
block reuptake of serotonin and norepinephrine
treat depression, anxiety, enuresis in children, ocd, eating disorders
do not give to people with cardiac disease, causes sedation and anticholinergic effects
Amitriptyline, nortriptyline, imipramine, desipramine, clomipramine, doxepin, amoxapine.
Drugs that affect GABA
Centrally acting muscle relaxants
tricyclic antidepressants
atypical antipsychotics
Block the reuptake of NE and 5HT, treats depression, one kind treats fibrmyalgia
SE: increased bp, insomnia
do not stop suddenly
effexor, cymbalta, pristiq
tricyclic antidepressants
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
Norepinephrine and Serotonin Specific Agonists
Serotonin Agonist Reuptake Inhibitor
Treat glaucoma, improve GI/urinary bladder tone
Acetylcholine, Pilocarpine, Methacholine, Bethanechol
Cholinergic blockers
Muscarinic Agonists
2 of 19 3/11/2021, 3:30 PM 8.
9.
10.
11.Adrenergic agonists
Drugs that affect GABA
Decrease warfarin dose
Test for gene VCORC1 mutation
CYP2C9
alpha 2 agonists
NSAIDS
Aspirin
medication that exerts analgesic and anti-inflammatory actions
Treats fever, pain, rheumatoid arthritis, osteoarthritis, gout, dysmenorrhea, tendinitis
Anorexiants
Aspirin
NSAIDS
Lithium
Not always necessary to have a prescription
Loperamide, diphenoxylate and cough medicine with less than 200mg/100 ml pregabalin
Cholinergic blockers
Schedule V
Dopaminergics
Anorexiants
Treat parkinsons by enhancing dopamine
do not give to schizophrenic patients
levodopa (sinemet)
stand up slowly, inhibited by protein
Beta 1 Antagonist
3 of 19 3/11/2021, 3:30 PM
