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NSG 6006 Predictor Exam VERIFIED

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NSG 6006 Predictor Exam VERIFIED 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. a. Cytochrome p450 system is a series of enzymes used to metabolize medications. b. Drugs that cause CYP450 metabolic drug interactions are referred to as either inhibitors or inducers. Inducers increase CYP450 enzyme activity by increasing enzyme synthesis c. Inhibitors block the metabolic activity of one or more CYP450 enzymes 2. Describe the affect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound. a. Album

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