Chamberlain College of Nursing NR 601
Final Exam Possible Questions with
Answers (Study Guide)
Chamberlain College of Nursing NR 601 Final Exam Possible
Questions with Answers (Study Guide)
MULTIPLE CHOICE
1. Factors that affect the pharmacokinetics of lipophilic medications in older adults
include:
a. greater adipose tissue ratio to body mass.
b. decreased total body water.
c. increased glomerular filtration rate.
d. increased creatinine clearance.
ANS: A
Older adults have a higher ratio of adipose (fat) tissue where lipophilic (fat-soluble) medications
can be stored thus resulting in a potential for an accumulation of the medication and potentially
fatal overdoses. Older adults have a decrease in lean body mass and an increase in fat. An
increased body mass would not affect lipophilic medication absorption. Older adults have a
decreased glomerular filtration rate, which begins to decline as early as age 25. Older adults have
a decrease in overall kidney function.
DIF: Cognitive Level: Remembering REF: p. 103
TOP: Integrated Process: Teaching/Learning
MSC: Client Needs: Health Promotion and Maintenance
2. Which pharmacokinetic/pharmacodynamic parameter does the aging process least
affect?
a. Absorption
b. Distribution
c. Metabolism
d. Excretion
ANS: A
There is no conclusive evidence that the absorptive process is changed appreciably in older
adults. Distribution, metabolism, and excretion are all affected significantly by aging.
DIF: Cognitive Level: Remembering REF: p. 107
TOP: Integrated Process: Teaching/Learning
MSC: Client Needs: Health Promotion and Maintenance
, 3. What factor is an important contribution to polypharmacy in older adults?
a. Inadequate communication among medical care providers
b. Implementation of Medicare Part D prescription drug benefit
c. Use of generic medications
Final Exam Possible Questions with
Answers (Study Guide)
Chamberlain College of Nursing NR 601 Final Exam Possible
Questions with Answers (Study Guide)
MULTIPLE CHOICE
1. Factors that affect the pharmacokinetics of lipophilic medications in older adults
include:
a. greater adipose tissue ratio to body mass.
b. decreased total body water.
c. increased glomerular filtration rate.
d. increased creatinine clearance.
ANS: A
Older adults have a higher ratio of adipose (fat) tissue where lipophilic (fat-soluble) medications
can be stored thus resulting in a potential for an accumulation of the medication and potentially
fatal overdoses. Older adults have a decrease in lean body mass and an increase in fat. An
increased body mass would not affect lipophilic medication absorption. Older adults have a
decreased glomerular filtration rate, which begins to decline as early as age 25. Older adults have
a decrease in overall kidney function.
DIF: Cognitive Level: Remembering REF: p. 103
TOP: Integrated Process: Teaching/Learning
MSC: Client Needs: Health Promotion and Maintenance
2. Which pharmacokinetic/pharmacodynamic parameter does the aging process least
affect?
a. Absorption
b. Distribution
c. Metabolism
d. Excretion
ANS: A
There is no conclusive evidence that the absorptive process is changed appreciably in older
adults. Distribution, metabolism, and excretion are all affected significantly by aging.
DIF: Cognitive Level: Remembering REF: p. 107
TOP: Integrated Process: Teaching/Learning
MSC: Client Needs: Health Promotion and Maintenance
, 3. What factor is an important contribution to polypharmacy in older adults?
a. Inadequate communication among medical care providers
b. Implementation of Medicare Part D prescription drug benefit
c. Use of generic medications
