Understanding
Pathophysiology, 6th
Edition
,Chapter 01: Cellular Biology
Huether & McCance: Understanding Pathophysiology, 6th Edition
MULTIPLE CHOICE
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA with
histones. Which of the following would also be observed by the student?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its nucleus; thus,
the nucleus should be observed. A single circular chromosome called a prokaryote contains free-floating
nuclear material but has no organelles.
REF: p. 2
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
c. Secretion
d. Respiration
ANS: D
NURSINGTB.COM
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability involves
maintenance of a steady dynamic state, metabolic absorption provides nutrition, and secretion allows
for the synthesizing of new substances.
,REF: p. 2
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of the
genetic information be contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm
ANS: C
The region of the cell that contains genetic material, including a large amount of ribonucleic acid, most
of the DNA, and DNA-binding proteins, is the nucleolus, which is located within the cell’s nucleus.
Mitochondria is associated with cellular respiration, while ribosomes are involved with protein
manufacturing. Cytoplasm is a fluid filling that is a component of the cell.
REF: p. 2
4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the layer
itself?
a. Peripheral membrane proteins
b. Integral membrane proteins
c. Glycoproteins
d. Cell adhesion molecules
ANS: B
Proteins directly attached to the membrane bilayer can be removed by the action of integral membrane
proteins that dissolve the bilayer. Peripheral membrane proteins reside at the surface while cell
adhesion molecules are on the outside of the membrane. Glycoprotein marks cells and does not float.
REF: p. 7
, 5. Which of the following can bind to plasma membrane receptors?
a. Oxygen
b. Ribosomes
c. Amphipathic lipids
d. Ligands
ANS: D
Ligands are the only specific molecules that can bind with receptors on the cell membrane.
REF: p. 9
6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in the
extracellular matrix would suNppoRrt thIe dGiagnBo.siCs ofMmetastatic cancer?
a. Decreased fibronectin
b. Increased collagen
c. Decreased elastin
d. Increased glycoproteins
ANS: A
Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing them to travel
or metastasize.
REF: p. 10
7. Which form of cell communication is used to relate to other cells in direct physical contact?
a. Cell junction
b. Gap junction
c. Desmosome
d. Tight junction
ANS: A
Cell junctions hold cells together and permit molecules to pass from cell to cell.
Pathophysiology, 6th
Edition
,Chapter 01: Cellular Biology
Huether & McCance: Understanding Pathophysiology, 6th Edition
MULTIPLE CHOICE
1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA with
histones. Which of the following would also be observed by the student?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its nucleus; thus,
the nucleus should be observed. A single circular chromosome called a prokaryote contains free-floating
nuclear material but has no organelles.
REF: p. 2
2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse
describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
c. Secretion
d. Respiration
ANS: D
NURSINGTB.COM
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability involves
maintenance of a steady dynamic state, metabolic absorption provides nutrition, and secretion allows
for the synthesizing of new substances.
,REF: p. 2
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of the
genetic information be contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm
ANS: C
The region of the cell that contains genetic material, including a large amount of ribonucleic acid, most
of the DNA, and DNA-binding proteins, is the nucleolus, which is located within the cell’s nucleus.
Mitochondria is associated with cellular respiration, while ribosomes are involved with protein
manufacturing. Cytoplasm is a fluid filling that is a component of the cell.
REF: p. 2
4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving the layer
itself?
a. Peripheral membrane proteins
b. Integral membrane proteins
c. Glycoproteins
d. Cell adhesion molecules
ANS: B
Proteins directly attached to the membrane bilayer can be removed by the action of integral membrane
proteins that dissolve the bilayer. Peripheral membrane proteins reside at the surface while cell
adhesion molecules are on the outside of the membrane. Glycoprotein marks cells and does not float.
REF: p. 7
, 5. Which of the following can bind to plasma membrane receptors?
a. Oxygen
b. Ribosomes
c. Amphipathic lipids
d. Ligands
ANS: D
Ligands are the only specific molecules that can bind with receptors on the cell membrane.
REF: p. 9
6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in the
extracellular matrix would suNppoRrt thIe dGiagnBo.siCs ofMmetastatic cancer?
a. Decreased fibronectin
b. Increased collagen
c. Decreased elastin
d. Increased glycoproteins
ANS: A
Only a reduced amount of fibronectin is found in some types of cancerous cells, allowing them to travel
or metastasize.
REF: p. 10
7. Which form of cell communication is used to relate to other cells in direct physical contact?
a. Cell junction
b. Gap junction
c. Desmosome
d. Tight junction
ANS: A
Cell junctions hold cells together and permit molecules to pass from cell to cell.
