BIO 3180 /BIO3180 MYSTERY OF THE MASSIVELY MUSCULAR MYOSTATIN BULL

BIO 3180 /BIO3180 MYSTERY OF THE MASSIVELY MUSCULAR MYOSTATIN BULL Transcribe and translate the portion of the myostatin gene from Figure 5. Assume the bottom strand is the template strand with the understanding that the promoter region in the DNA and the start and stop codons in the mRNA are not depicted (present in the sequence on either end of what is shown). 1. Holstein mRNA sequence: _____________________________________ 2. Holstein polypeptide sequence: ________________________________ Arnold: Now that we’ve gone through the process, I think I understand how DNA is transcribed and the resulting mRNA is translated into protein. I would like to understand a little bit more about how the myostatin protein works in cells so that I can understand how a mutation might result in muscle hypertrophy.” Jack: I’ll email Professor Ricks about this, I think we may need her help in understanding the role of myostatin in cells. Email from Professor Ricks: Jack, I am proud that you are delving deeper into understanding the role of myostatin. I will just give you a brief overview of its function in cells. Myostatin is involved in inhibiting muscle growth by binding to other proteins called receptors on the surface of skeletal muscle cells. When the myostatin protein is not functional, the result is increased muscle mass. I hope this is enough information for you to work with. Sincerely, Professor Vanessa Ricks