Pharmacology – End of chapter questions – EXAM 1
Module 1
Chapter 2 – Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics
1. Which components of pharmacokinetics does the nurse need to understand before
administering a drug? (select all that apply)
a. Drugs with a smaller volume of drug distribution have a longer half-life
b. Oral drugs are dissolved through the process of pinocytosis
c. Patients with kidney disease may have fewer protein-binding sites and are at risk
for drug toxicity
d. Rapid absorption decreases the bioavailability of the drug
e. When the drug metabolism rate is decreased, excess drug accumulation can occur,
which can cause toxicity
2. The nurse will question the health care provider if a drug with a half-life (t ½) of more
than 24 hours is ordered to be given more than how often?
a. Once daily
b. Every other day
c. Twice weekly
d. Once weekly
3. The nurse is explaining drug action to a nursing student. Which statement made by the
nurse is correct?
a. Water-soluble and ionized drugs are quickly absorbed
b. A drug not bound to protein is an inactive drug
c. Most receptors are found under the cell membrane
d. Toxic effects can result if the through level is low
4. A native American patient is newly diagnosed with type 2 diabetes mellitus and is
prescribed the antidiabetic drug metformin 500 mg per os with morning and evening
meals. Which statement best indicates to the nurse that the patient will adhere to the
therapeutic regimen?
a. I will no longer put sugar on my cereal because that will help me be healthier
b. If I take this medicine, I will feel better soon and won’t have to take it anymore
c. To reduce the possibility of damage to my body, I must take the medicine as
scheduled
d. I have diabetes because of my ancestry, so there’s not much I can do about it
5. The nurse is aware that the rate of absorption can be changed by which actions? (select
all that apply)
a. Modifying gastric emptying time
b. Changing gastric pH
c. Decreasing inflammation
d. Forming drug complexes
e. Eating too slowly
1
, 6. The nurse is reviewing a patient’s medications as part of patient teaching. The nurse is
aware that which drug is least likely to cause photosensitivity?
a. Penicillins
b. Sulfonamides
c. Sulfonylureas
d. Thiazides
7. The nurse is meeting with a community group about medication safety. The nurse must
emphasize that patients at high risk for drug interactions include which groups? (select all
that apply)
a. Older patients
b. Patients with chronic health conditions
c. Patients taking three or more drugs
d. Patients dealing with only one pharmacy
e. Patients covered by Medicare or Medicaid
8. The nurse recognizes that when a patient takes a hepatic enzyme inducer, the dose of
warfarin is usually modified in which way?
a. It is increased
b. It is decreased
c. It remains the same
d. It is unpredictable
9. The nurse is describing to a patient the synergistic effects of two of his medications.
Which statement by the nurse is correct about the synergistic drug effect?
a. Two drugs have antagonistic effects on each other
b. The action of a drug is nullified by another thing
c. One drug act as an antidote to the side effects of another drug
d. A greater effect is achieved when two drugs are combined
10. A patient asks the nurse about drug interactions with over-the-counter prescriptions. What
is the nurse’s best response?
a. Discuss this with the health care provider
b. There are not many interactions, so don’t worry about it
c. Read the labels carefully, and check with your health care provider
d. Avoid over-the-counter preparations
2
Module 1
Chapter 2 – Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics
1. Which components of pharmacokinetics does the nurse need to understand before
administering a drug? (select all that apply)
a. Drugs with a smaller volume of drug distribution have a longer half-life
b. Oral drugs are dissolved through the process of pinocytosis
c. Patients with kidney disease may have fewer protein-binding sites and are at risk
for drug toxicity
d. Rapid absorption decreases the bioavailability of the drug
e. When the drug metabolism rate is decreased, excess drug accumulation can occur,
which can cause toxicity
2. The nurse will question the health care provider if a drug with a half-life (t ½) of more
than 24 hours is ordered to be given more than how often?
a. Once daily
b. Every other day
c. Twice weekly
d. Once weekly
3. The nurse is explaining drug action to a nursing student. Which statement made by the
nurse is correct?
a. Water-soluble and ionized drugs are quickly absorbed
b. A drug not bound to protein is an inactive drug
c. Most receptors are found under the cell membrane
d. Toxic effects can result if the through level is low
4. A native American patient is newly diagnosed with type 2 diabetes mellitus and is
prescribed the antidiabetic drug metformin 500 mg per os with morning and evening
meals. Which statement best indicates to the nurse that the patient will adhere to the
therapeutic regimen?
a. I will no longer put sugar on my cereal because that will help me be healthier
b. If I take this medicine, I will feel better soon and won’t have to take it anymore
c. To reduce the possibility of damage to my body, I must take the medicine as
scheduled
d. I have diabetes because of my ancestry, so there’s not much I can do about it
5. The nurse is aware that the rate of absorption can be changed by which actions? (select
all that apply)
a. Modifying gastric emptying time
b. Changing gastric pH
c. Decreasing inflammation
d. Forming drug complexes
e. Eating too slowly
1
, 6. The nurse is reviewing a patient’s medications as part of patient teaching. The nurse is
aware that which drug is least likely to cause photosensitivity?
a. Penicillins
b. Sulfonamides
c. Sulfonylureas
d. Thiazides
7. The nurse is meeting with a community group about medication safety. The nurse must
emphasize that patients at high risk for drug interactions include which groups? (select all
that apply)
a. Older patients
b. Patients with chronic health conditions
c. Patients taking three or more drugs
d. Patients dealing with only one pharmacy
e. Patients covered by Medicare or Medicaid
8. The nurse recognizes that when a patient takes a hepatic enzyme inducer, the dose of
warfarin is usually modified in which way?
a. It is increased
b. It is decreased
c. It remains the same
d. It is unpredictable
9. The nurse is describing to a patient the synergistic effects of two of his medications.
Which statement by the nurse is correct about the synergistic drug effect?
a. Two drugs have antagonistic effects on each other
b. The action of a drug is nullified by another thing
c. One drug act as an antidote to the side effects of another drug
d. A greater effect is achieved when two drugs are combined
10. A patient asks the nurse about drug interactions with over-the-counter prescriptions. What
is the nurse’s best response?
a. Discuss this with the health care provider
b. There are not many interactions, so don’t worry about it
c. Read the labels carefully, and check with your health care provider
d. Avoid over-the-counter preparations
2
