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IEB Grade 12 DNA - code of life notes and summary

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-




↳ ' '
nucleic acids molecules of life store information that controls cellular and the
,
the
activity
organism development by controlling ,
the Synethesis of proteins

proteins (enzymes ) control the chemical processes inside the cell
p
two nucleic acids found in cells :






Deoxy ribonucleic acid ( DNA )
C
o

Ribonucleic acid (RNA )


OH
① Deoxy ribonucleic acid -
DNA

↳ found
mainly in the nucleus of the cell where it forms part of the chromosomes in the chromatin

network


extra nuclear DNA -


small amounts of DNA found outside the nucleus in MitchOndria and

Chro IOP lasts

↳ two strands twist to form stable 3D double helix
long a ,




how is the double helix made up ?





The Strands of the ladder sugar 1phosphate
-




outer 2 formed by a chain of
are
alternating
links The bonds between the sugar and phosphate molecules are
.



strong
The rungs of the ladder are formed from pairs of bases linked by weak
hydrogen bonds
-




-




The base pairs are attached to the sugar molecules


small units (monomers ) i.e
molecule is a
long chain (
polymer ) made up of .




building blocks called

nucleotides


each nucleotide is made up of a :




sugar molecule
deoxyribose (s )

-






phosphate molecule ( P)

nitrogenous base which be


:
may
adenine CA)
-




thymine CT )
-




guanine (G)
-




cytosine CC )
-

, ↳
4 bases are the foundation of code cells on how to
the
genetic ,
instructing synthesise
enzymes and other proteins
↳ 4
different nitrogenous bases =
4 different nucleotides



How do these 4 base
pairs link up ?
↳ the
shape and size of the 4 bases differ so that :




adenine will uracil bonds T A= U
only bond with
thymine by means of 2
hydrogen A




eg
=
, ,




of 3 hydrogen bonds C C-
cytosine will
only bond with
guanine by means
eg =


,




How are the base pairs classified ?
↳ there are 2
groups of nitrogenous bases purines and pyrimidines :
-




made of 2 fused rings of nitrogen and (guanine and adenine )
purines are carbon hydrogen atoms



,




pyrimidines are made of I ring of similar atoms and are much smaller than purines (thymine



,




and uracil )
cytosine
↳ a
base pair is made of one purine and one pyrimidine
↳ all 4 nucleotides are the same in plants and animals


How do ?
organisms differ
↳ the which determines the code of
sequence of the nucleotides , genetic an
organism


Role of DNA
↳ DNA molecules :



in each cell in the form of
carry hereditary information genes








provide a blueprint for an organism 's growth and development by coding for protein synthesis

can replicate so that a
copy of the genetic information is passed on to each
daughter
cell
during cell division ,
which ensures that the genetic code is passed on from generation

to generation
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