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Diabetes Mellitus

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Lecture notes on Diabetes Mellitus

Institution
Manchester Metropolitan University (MMU)
Course
Blood Science (6H5Z1003)








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Institution
Manchester Metropolitan University (MMU)
Study
Manchester Metropolitan University
Course
Blood Science (6H5Z1003)
All documents for this subject (49)

Document information

Uploaded on
February 13, 2022
Number of pages
4
Written in
2021/2022
Type
Class notes
Professor(s)
Dr amanda unsworth
Contains
All classes

Subjects

  • blood
  • science
  • diabetes mellitus
  • human
  • bioscience
  • biomedical
  • biology

Content preview

Blood [Glucose]:
- Random: <10 mmol/L
- Fasting 3.5-5.5 mmol/L
- Essential for brain function
- Regulation via insulin and glucagon

Functions of insulin:
1. Stimulatory
a. Glucose uptake by muscle / adipose
b. Glycolysis
c. Glycogen synthesis
d. Protein synthesis
e. Cellular uptake of potassium / phosphate
2. Inhibitory:
a. Gluconeogenesis
b. Glycogenolysis
c. Ketogenesis
d. Proteolysis

Blood Glucose regulation:




Diabetes Mellitus: a syndrome characterised by hyperglycemia due to an absolute or relative deficiency of and/or
resistance to insulin

Diabetes - IDF estimates:
- 422 million diabetics in 2014
- 592 million diabetics in 2035
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