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NGR 5141 Patho exam 1 Study guide

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Patho exam 1 Study guide The mammary glands enlarge during pregnancy primarily as a consequence of:  Hormonal hyperplasia The consequences of hypoxic injury include:  decreased production of ATP, increased intracellular lactate, decreased protein synthesis Active transport occurs only across membranes that:  use energy generated by cellular metabolism and have receptors that are capable of recognizing and binding with the substances to be transported In chemical injury, membrane destruction results from:  lipid peroxidation, reactive free radicals, direct toxicity Asphyxial injuries include:  suffocation, strangulation, chemical injuries, drowning Atypical hyperplasia is another name for:  Dysplasia Muscular hypertrophy may involve:  an increase in muscle cell size, and an increase in protein synthesis The single most common cause of cellular injury is:  hypoxic injury Melanin is synthesized by epidermal cells called ____________ and accumulates in epidermal cells called _____________.  melanocytes, keratinocytes

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Patho exam 1 Study guide

The mammary glands enlarge during pregnancy primarily as a consequence of:

 Hormonal hyperplasia

The consequences of hypoxic injury include:

 decreased production of ATP, increased intracellular lactate, decreased protein synthesis

Active transport occurs only across membranes that:

 use energy generated by cellular metabolism and have receptors that are capable of recognizing and binding with the substances to be
transported

In chemical injury, membrane destruction results from:

 lipid peroxidation, reactive free radicals, direct toxicity

Asphyxial injuries include:

 suffocation, strangulation, chemical injuries, drowning

Atypical hyperplasia is another name for:

 Dysplasia

Muscular hypertrophy may involve:

 an increase in muscle cell size, and an increase in protein synthesis

The single most common cause of cellular injury is:

 hypoxic injury

Melanin is synthesized by epidermal cells called ____________ and accumulates in epidermal cells called _____________.

 melanocytes, keratinocytes

Compared with normal aerobic metabolism, cells that use anaerobic metabolism produce _______ ATP and _______ lactic acid.

 Less, more

Free radicals can be initiated in cells by:

 ultraviolet light, normal metabolic processes, metabolism of drugs

Cells that are particularly susceptible to ionizing radiation are those of the:

 gastrointestinal tract, bone marrow, lymph nodes, fetus

After ovulation the uterine endometrial cells divide under the influence of estrogen; this is an example of:

 Hormonal Hyperplasia

Proteins facilitate transport across membranes by serving as:

 Receptors, enzymes, transporters

Acute cellular swelling during ischemia is reversible if _________ is supplied quickly.

 Oxygen

What is the recurrence risk of this autosomal dominant disease for their next child? 50%

A somatic cell that does not contain a multiple of 23 chromosomes is called: an aneuploid cell

Which of the following are true about Huntington Disease?

 It is an age-dependent penetrance and A key characteristic is progressive dementia.

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