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Summary Drug allergy and anaphylaxis

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Describes in detail how to recognise drug allergy and anaphylaxis, also talks about how to manage these patients.

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Uploaded on
December 31, 2021
Number of pages
7
Written in
2021/2022
Type
Summary

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Drug allergy and anaphylaxis
Allergy status
Distinguishing allergic reactions
Cross reacting drugs
Risk factors
Treatment
Patient follow up
Investigations


Allergy status
You should take a full allergy history before prescribing any medications. It can be
obtained from:

Patient Care home

Carer Medical notes

GP Summary care records

Community pharmacist

When taking an allergy history you
should confirm and document:

All current and any recent drugs
(OTC drugs, herbal drugs and any
injections.)

The generic name for the drug
suspected to cause a reaction

The exact signs, symptoms and the
severity of the allergic reaction

When the reaction occured



Drug allergy and anaphylaxis 1

, How long the drug was taken before
the reaction occured

Whether the allergy is a first hand
recollection

Before prescribing for a patient check:

The drug allergy box on the drug chart or electronic system

Red drug allergy band

Medical notes for documented allergies

If re-writing drug chart ensure to transcribe allergy status

Document allergy status in medical notes, discharge prescriptions, discharge letters
and primary care referral information.




Distinguishing allergic reactions
Type 1 allergic reactions occur within
minutes to 2 hours of exposure to the
triggering drug. It may not always occur
with the first dose of the drug given.

Symptoms can occur very rapidly with
parenteral drug, the median time to
cardiac arrest in fatal drug induced
anaphylaxis is 5 minutes.

Symptoms include:

Urticaria (can arise due to infection
so determine whether it started
before or after drug)

Itching

Hypotension

Angioedema (ACE-inhibitors can
cause pure angioedema, can result


Drug allergy and anaphylaxis 2
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