Concept Check Chapter 19 Silverthorn Questions:
1. Ion regulation is a key feature of kidney function. What happens to the resting
membrane potential of a neuron if extracellular K+ levels decrease? [p.285]
2. What happens to the force of cardiac contraction if plasma Ca 2+ levels decrease
substantially? [p.502]
3. If net filtration out of glomerular capillaries occurs, then you know that capillary
hydrostatic pressure must be (greater than/less than/equal to) capillary colloid
osmotic pressure. [p.533]
4. If net reabsorption into peritubular capillaries occurs, then capillary hydrostatic
pressure must be (greater than/less than/equal to) the capillary colloid osmotic
pressure.
5. Name one way in which filtration and secretion are alike. Name one way in which
they differ.
6. A water molecule enters the renal corpuscle from the blood and ends up in the urine.
Name all the anatomical structures that the molecule passes through on its trip to
the outside world.
7. What would happen to the body if filtration continued at a normal rate but
reabsorption dropped to half the normal rate?
8. Why is the osmotic pressure of plasma in efferent arterioles higher than that in
afferent arterioles?
9. If a hypertensive person’s blood pressure is 143/107 mm Hg, and mean arterial
pressure = diastolic pressure + 1/3 the pulse pressure, what is this person’s mean
arterial pressure? What is this person’s GFR according to Figure 19.6b?
10. If systemic blood pressure remains constant but the afferent arteriole of a nephron
constricts, what happens to renal blood flow and GFR in that nephron?
11. A person with cirrhosis of the liver has lower-than-normal levels of plasma proteins
and consequently a higher-than-normal GFR. Explain why a decrease in plasma
protein concentration causes an increase in GFR.
12. If plasma creatinine = 1.8 mg/100 mL plasma, urine creatinine = 1.5 mg/mL urine, and
urine volume is 1100 mL in 24 hours, what is the creatinine clearance? What is GFR?
Concept Check chapter 19 Answers:
1. Hyperpolarizes (becomes more negative)
2. Force of contraction decreases
1. Ion regulation is a key feature of kidney function. What happens to the resting
membrane potential of a neuron if extracellular K+ levels decrease? [p.285]
2. What happens to the force of cardiac contraction if plasma Ca 2+ levels decrease
substantially? [p.502]
3. If net filtration out of glomerular capillaries occurs, then you know that capillary
hydrostatic pressure must be (greater than/less than/equal to) capillary colloid
osmotic pressure. [p.533]
4. If net reabsorption into peritubular capillaries occurs, then capillary hydrostatic
pressure must be (greater than/less than/equal to) the capillary colloid osmotic
pressure.
5. Name one way in which filtration and secretion are alike. Name one way in which
they differ.
6. A water molecule enters the renal corpuscle from the blood and ends up in the urine.
Name all the anatomical structures that the molecule passes through on its trip to
the outside world.
7. What would happen to the body if filtration continued at a normal rate but
reabsorption dropped to half the normal rate?
8. Why is the osmotic pressure of plasma in efferent arterioles higher than that in
afferent arterioles?
9. If a hypertensive person’s blood pressure is 143/107 mm Hg, and mean arterial
pressure = diastolic pressure + 1/3 the pulse pressure, what is this person’s mean
arterial pressure? What is this person’s GFR according to Figure 19.6b?
10. If systemic blood pressure remains constant but the afferent arteriole of a nephron
constricts, what happens to renal blood flow and GFR in that nephron?
11. A person with cirrhosis of the liver has lower-than-normal levels of plasma proteins
and consequently a higher-than-normal GFR. Explain why a decrease in plasma
protein concentration causes an increase in GFR.
12. If plasma creatinine = 1.8 mg/100 mL plasma, urine creatinine = 1.5 mg/mL urine, and
urine volume is 1100 mL in 24 hours, what is the creatinine clearance? What is GFR?
Concept Check chapter 19 Answers:
1. Hyperpolarizes (becomes more negative)
2. Force of contraction decreases
