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Exam (elaborations) N5315 Advanced Pathophysiology Inflammation, Altered Immunity And Infection Core Concepts Objectives With Advanced Organizers (NURS 5315)

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1. Examine the structure and function of the immune system. • Evaluate how the normal function of T-lymphocyte and B-lymphocyte cells differ. • T-lymphocyte: (mature in thymus) provide weapons to act antigens. Some kill virus-infected cells directly, some help B- cells make antibodies which circulate to bind to antigens (4 types) • B-lymphocyte: (mature in bone marrow) With help of T cells, B-cells make Y shaped proteins called antibodies that stick to antigens on the surface, stopping them and then creating clumps that alert your body to the presence of intruders. Your body then starts to make toxic substances to fight them. Phagocytes engulf and then destroy antibody-covered antigens

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