NCLEX RN A graded ( A)
1 A client exposed to Mycobacterium tuberculosis starts on chemoprophylaxis. The nurse provides what instruction to the client? Correct answer: 1 To prevent active tuberculosis after exposure, the client is initiated on a single agent regimen, usually isoniazid (INH). For newly diagnosed active disease (option 2), a combination of antitubercular agents is used for at least the first several weeks: isoniazid (INH), rifampin (Rifadin), and pyrazinamide (Tebrazid). The combination therapy lessens the risk of drug resistance (option 3). Except for streptomycin, which is for IM use, the antitubercular agents are administered orally (option 4). The critical words in the stem of the question are exposed and chemoprophylaxis. Differentiate exposure from infection as the key concept being tested. Recall that if active infection requires multi‐drug therapy, exposure can be managed with a single agent alone
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