Summary NR 565 Final Review - A Comprehensive Review of Week 5-8 Content for NR 565 Final

NR 565 Final Review - A Comprehensive Review of Week 5-8 Content for NR 565 Final. NR565 Week 5 Chapter 24: Drugs used in treating infectious diseases (p. 692-760)Antimicrobial resistance • Causes of drug resistance o Recent use of antibiotics o Overuse of broad-spectrum antibiotics o Age younger than 2 years or older than 65 years o Daycare center attendance o Exposure to young children o Multiple medical comorbidities o Immunosuppression • Every antibiotic class has resistance organisms. Week 7 & 8 Antacids: weak bases that react with hydrochloric acid to form salt & water. -Neutralize Gastric Acidity (causes ^pH of the stomach and duodenal bulb) -Inhibit proteolytic activity of pepsin -Increase lower esophagealsphincter tone -ALL antacids are contraindicated in the presence ofsevere abdominal pain of unknown cause, especially if accompanied by fever -HIGH SODIUM content: pts w/ HTN. CHF need to use low sodium preparation -Concurrent administration with enteric-coated drugs, destroysthe coating= alters absorption, ^ the risk for adverse effects -Administrations should be separated by at least 2 hours to decrease interactions