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samenvatting epithelen

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Samenvatting o.b.v. het hoofdstuk epithelen in het boek functionele histologie en de cursus.

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Hoofdstuk epithelen
Uploaded on
May 14, 2021
Number of pages
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Written in
2020/2021
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Histologie: epithelen
Algemeen
 Beschermen van onderliggende weefsel
o Bedekken lichaamsppervlak
o Lijnen lichaamsholgen en kanalen af
 Regulatie van opname en afgifte van stoffen
 Vormt klieren (klierepitheel)
 Gespecialisserde epitheliale weefsels
 Bestaan uit 1 of meer lagen van epitheelcellen
 Cellen sluiten nauw aaneen
 Zeer weinig extracellulaire matrix (LM: dicht opeengeplakte cellen, EM: nauwe spleten)
 Cellen zijn verbonden met elkaar door intercellulaire verbindingen
 Basaalmembraan = afgrenzing van onderliggende bindweefsellaag
 Bevat GEEN bloedvaten


Bloedvoorziening
Bloedvaten dringen nooit binnen in epitheel weefsel
-> epitheel is dus afhankelijk van diffusie van zuurstof en VS van onderliggende weefsels

Epitheelcel
Cytoskelet van epitheelcel bestaat uit keratine

KERATINE
 Keratine-eiwitten worden in alle epitheelcellen geproduceerd
 Specifiek type keratine in specifieke epitheelcel
 Kunnen keratine-filamenten vormen (invermediaire filamenten)
 Belangrijk voor keratinisering en verhoorning

CELPOLARITEIT
=> epitheelcellen zijn gepolariseerd: apicale, basale, laterale domeinen zijn functioneel verschillend
Epitheel gesteund door onderliggend basaalmembraan




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