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NES TO GENOMES 6TH EDITION BY HA
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RTWELL
Genetics From Genes To Genomes 6th Edition
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Hartwell Test Bank n n
Hartwell
Chaptern1n Genetics:nThenStudynofnBiologicalnInformation
1) HowndoesnDNAnstructurenrelatentonitsnfunction?
- ThenordernofnnucleotidesninnanDNAnstrandnspecifiesnthenordernofnaminonacidsnin
naIprotein.
2) WhatnisnandifferencenbetweennthenstructurenofnDNAnandnproteins?
- DNAnisncomposednofnnucleotidesnandnproteinsnarencomposednofnaminonacids.
3) Angenomencannbenbestndescribednas
- thenDNAninnallnchromosomesninnancell.
4) WhatnisnthendifferencenbetweennthenfunctionnofnDNAnandnthenfunctionnofnproteins?
- DNAnstoresngeneticninformationnandnproteinsnperformnmostncellularnfunctions.
5) Whichnstatementnsupportsnthentheorynthatnallnorganismsnarenrelated?
- Thengeneticncodenisnalmostnuniversal.
6) Newngenesnarenthoughtntonarisenbynwhichnmechanism?
- Genenduplicationnfollowednbyndivergencenduentonmutation.
7) Whatnisnthenmostnlikelynwaynanmutationninnonengenencannconvertnonenbodynpartnto
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL
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another?
- Thenmutatedngenenencodesnanproteinnthatnaffectsnthenexpressionnofnmanynother
genes.
8) Anrecentntechnicalnadvancementnthatnhasnacceleratednthenstudynofngenomesnisnthe
nabilityto
- sequencenlargencomplexngenomesnrapidlynandninexpensively.
9) Whatnisnthendifferencenbetweenngeneticndissectionnandngenomensequencing?
- Geneticndissectionnrevealsninformationnaboutnonengenenatnantimenandnge
nomesequencingnrevealsninformationnaboutnallnthengenesninnangenomenatnonce.
10) Currently,nwhatninformationncannbenobtainednfromnsequencingnannindividual'sngenome?
- Informationnaboutngenenvariantsnthatnpredisposenanpersonntonandisease,nsuch
nasIcancer.
11) Whichnisnnotnanpotentialnproblemnofnallowingnthengenomicnsequencesnofnindividuals
ntobecomenwidelynavailable?
- Advancesnleadingntonhealthiernlivesnfornsomenpeople.
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12) OnenstrandnofnDNAnhasnthensequencen5′nGGTCTAn3′.nWhatnisnthensequencenofnthenothe
rstrand?
- 5′nTAGACCn3′
13) WhichnstatementnisntruenaboutnthenstructurenofnDNA?
- ThentwonstrandsnofnanDNAnmoleculenarenheldntogethernbynbasenpairing.
14) Thensizenofnthenmousen(M.nmusculus)ngenomenisn2700nmegabasesn(Mb)n andn itn contain
snaboutn25,000ngenesnarrangednonn40nchromosomes.nIfnthengenesnarenevenlyndistributedn
onnchromosomesninnthenmouse,nwhatnisnthenaveragennumbernofngenesnpernchromosome?
-n625
15) Whichnstatementnaboutnthenstructurenofnproteinsnisnfalse?
- Mostnproteinsnconsistnofntwonaminonacidnpolymersnattachedntogethernbynhydrogen
nbonding.
16) WhichnisnanstructuralnfeaturensharednbynDNA,nRNA,nandnproteins?
- Thenordernofnmonomersnisnimportantnfornfunction.
17) AnsegmentnofnanproteinnhasnthenaminonacidnsequencenSer—Gly—
Leu.nIsnitnpossiblentoinfernthensequencenofnthenRNAnthatnencodesnthisnaminonacidnsequen
ce?
No;nmorenthannonentypenofnRNAn(morenthannonenbasensequence)ncouldnencodenthisnaminoaci
dnsequence.
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18) AnsequencenofnbasesninnthenmiddlenofnannRNAnusedntonencodenanpolypeptidenhasnthense
quencenUUA—AUG—
CGU.nIsnitnpossiblentoninfernthensequencenofnthenaminonacidsnencodednbynthisnRNA?
- Yes,nthensequencenisnLeu—Met—Arg.
19) Mutationnofnanmousengenenresultsninnmicenthatnlacknheartnmuscle.nWhatncharacteristic
nwouldnyounexpectntonfindninnanhumanngenenthatnhasnancommonnoriginnwithnthisnmouseng
ene?
- Thenhumannandnmousengenesnwillnspecifynproteinsnwithnsimilarnamino
nacidsequences.
20) Anmousengenenwasnidentifiednandndeterminedntonbenrequirednfornformationnofnheart
nmuscle.nAngenenwithnansimilarnsequencenwasnidentifiedninnthenhumanngenome.nWhatne
xperimentncouldnscientistsndontondeterminenifnthenmousenandnhumanngenesnhavensimila
rfunctions?
- Thenscientistncouldnplacenthennormalnhumanngenenintonmutantnmicentonseenif
nheartmusclenformsninnthenmouse.
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL