Final Exam Advanced Pathophysiology, Pathophysiology Finals.pdf

Final Exam Advanced Pathophysiolo
nm nm nm


gy, Pathophysiology Finals
nm nm




physiologicnmjaundicenm-nmcorrectnmanswer✔ ✔ Anm3-
daynmoldnminfantnmisnmnotednmtonmhavenmanmmildlynmelevatednmunconjugatednmb
ilirubinnmlevelnmandnmicterus.nmYournmconcernnmisnmthatnmthisnmchildnmmaynmha
ve:
a.nmphysiologicnmjaundice
b.nmkernicterus
c.nmglucose-6-phosphatenmdehydrogenasenmdeficiency
d.nmpathologicnmjaundice


Lysosomesnm-nmcorrectnmanswer✔ ✔
Whichnmcellnmcomponentnmisnmcapablenmofnmcellularnmautodigestionnmwhenn
mitnmisnmreleasednmduringnmcellnminjury?



a.nmlysosomes
b.nmribosomesc.nmsmoothnmendoplasmi
cnmreticulum
d.nmgolginmcomplex


Whichnmcomponentnmofnmthenmcellnmproducesnmhydrogennmperoxidenm(H2O2)
nmbynmusingnmoxygennmtonmremovenmhydrogennmatomsnmfromnmspecificnmsubstr


atesnminnmannmoxidativenmreaction?

,A)nmlysosomes
B)nmperoxisomes
C)nmribosomes

D)nmoxyhydrosomesnm-nmcorrectnmanswer✔ ✔ Ans:nmB-nmperoxisomes


Containnmorganellesnmandnmcomplexnminternalnmmembranesnm-
nmcorrectnmanswer✔ ✔
Thenmdifferencenmbetweennmeukaryotesnmandnmprokaryotesnmisnmthatnmeukar
yotes:
a.nmallnmofnmthesenmanswersnmarenmcorrect
b.nmarenmsmallernminnmsize
c.nmcontainnmorganelles
d.nmhavenmnonmnuclearnmmembrane


Whatnmisnmanmconsequencenmofnmplasmanmmembranenmdamagenmtonmthenmmitoc
hondria?


A)nmenzymaticnmdigestionnmhaltsnmdeoxyribonucleicnmacidnm(DNA)nmsynthes
e
B)nminfluxnmofnmcalciumnmionsnmhaltsnmadenosinenmtriphosphatenm(ATP)nmpro
duction

,C)nmedemanmfromnmannminfluxnminnmsodiumnmcausesnmanmreductionnminnmATPnm
production
D)nmpotassiumnmshiftsnmoutnmofnmthenmmitochondria,nmwhichnmdestroysnmthenmi
nfrastructurenm-nmcorrectnmanswer✔ ✔ Ans:nmB-
nminfluxnmofnmcalciumnmionsnmhaltsnmadenosinenmtriphosphatenm(ATP)nmproduc


tion


Packagesnmproteinnmfornmsecretionnmtonmthenmoutsidenmofnmthenmcellnm-
nmcorrectnmanswer✔ ✔
WhichnmofnmthenmfollowingnmisnmfunctionnmofnmGolgi?
a.nmPackagesnmproteinnmfornmsecretionnmtonmthenmoutsidenmofnmthenmcell
b.nmProducesnmATPnmfornmcellnmfunction
c.nmContainsnmhydrolyticnmenzymes
d.nmIsnmthenmsitenmofnmproteinnmsynthesisnminnmanmcell


Whichnmstatementnmisnmanmdescriptionnmofnmonenmofnmthenmcharacteristicsnmofnm
apoptosis?


A)nmapoptosisnminvolvesnmprogrammednmcellnmdeathnmofnmscatterednmsingelnmc
ells
B)nmapoptosisnmisnmcharacterizednmbynmthenmswellingnmofnmthenmnucleusnmandnm
thenmcytoplasm
C)nmapoptosisnminvolvesnmunpredictablenmpatternsnmofnmcellnmdeath

, D)nmapoptosisnmresultsnminnmbenignnmmalignanciesnm-nmcorrectnmanswer✔
✔ Ans:nmA-
nmapoptosisnminvolvesnmprogrammed nmcellnmdeathnmofnmscatterednmsingelnmcell


s


Duringnmcellnminjurynmcausednmbynmhypoxia,nmsodiumnmandnmwaternmmovenmin
tonmthenmcellnmbecause:


A)nmduringnmcellnminjurynmcausenmbynmhypoxia,nmsodiumnmandnmwaternmmovenm
intonmthenmcellnmbecause:
B)nmthenmpumpnmthatnmtransportsnmsodiumnmoutnmofnmthenmcellnmcannotnmfuncti
onnmbecausenmofnmanmdecreasenminnmadenosinenmtriphosphatenm(ATP)nmlevels
C)nmthenmosmoticnmpressurenmisnmincreased,nmwhichnmpullsnmadditionalnmsodiu
mnmacrossnmthenmcellnmmembrane
D)nmoxygennmisnmnotnmavailablenmtonmbindnmwithnmsodiumnmtonmmaintainnmitnmo
utsidenmofnmthenmcellnm-nmcorrectnmanswer✔ ✔ Ans:nmC-
nmthenmosmoticnmpressurenmisnmincreased,nmwhichnmpullsnmadditionalnmsodiumn


macrossnmthenmcellnmmembrane




Isnmthenmsitenmofnmproteinnmsynthesisnminnmanmcellnm-nmcorrectnmanswer✔ ✔
Whichnmofnmthenmfollowingnmisnmfunctionnmofnmthenmroughnmendoplasmicnmre
ticulum?
a.nmContainsnmhydrolyticnmenzymes
b.nmIsnmthenmsitenmofnmproteinnmsynthesisnminnmanmcell