NURS 5315 UTA Exam 2 Questions and Correct Answers
Question 1
Complement
Correct Answer
Functions include bacterial lysis, vasodilation and increased vascular permeability, triggers mast cell degranulation,
chemotaxis, and opsonization.
Question 2
Prostacyclin
Correct Answer
Vasodilation, platelet aggregation (most effective one)
Question 3
Monocytopenia- definition and causes
Correct Answer
Decreased # of monocytes
From steroid use of HIV infection
Page 1 of 34
,Question 4
COX1
Correct Answer
Prostaglandin of arachidonic pathway. Provides gastroprotection, platelet aggregation, fluid/electrolyte balance
Question 5
CM of Hodgkin's Lymphoma
Correct Answer
Large painless lump/mass- usually on neck, eosinophilia, fever, weight loss, night sweats, pruritus, adenopathy,
thrombocytosis, leukocytosis, mediastinal or abdominal mass
Question 6
Arachidonic pathway purpose
Correct Answer
Synthesis of prostaglandins
Question 7
4th generation immunoassay
Correct Answer
"gold standard"
can test 10 days post exposure
can result negative, positive with HIV antibody, or positive without HIV antibody
Page 2 of 34
,Question 8
Effects of genetic mutation of CCR5 cell receptor
Correct Answer
Some people of European descent carry the CCR5 delta32 mutation. The mutation makes a person functionally resistant
to the HIV virus, and might be a cure for those individuals
Question 9
Prostaglandins
Correct Answer
Released when mast cells degranulate, are produced by the arachidonic pathway. Cause vasodilation, platelet
aggregation at site of injury, pain, and fever.
Question 10
discuss hemophilia A
Correct Answer
affects 1 in 5-10K males
sex linked recessive disease, deficient in factor VIII
normal platelets and PT, prolonged PTT, decreased factor VIII
CM: knee, elbow, and ankle bleeds, GI bleeds
Page 3 of 34
, Question 11
Alloimmunity and example of hypersensitivity
Correct Answer
When an individuals immune system reacts against antigens on the tissues of other members of the same species
Blood transfusions- causes clumping and lysis of RBC- fever, nausea, chills, low back pain, dark urine, hives, itching, SOB
Rh incompatibility- hemolytic disease of newborn with jaundice, give Rhogam within 72 hours of birth (Rh- mother with
Rh+ child)
Question 12
Discuss some clinical implications of solid organ transplant rejection
Correct Answer
rejection is an immune response, mostly T-cell mediated. Slow process, Type 4 hypersensitivity
Patients are highly susceptible to infections r/t use of immunosuppressants
Question 13
COX2
Correct Answer
Prostaglandin of arachidonic pathway. Responsible for pain, fever, renal protection, tissue repair, reproduction
development.
Page 4 of 34
Question 1
Complement
Correct Answer
Functions include bacterial lysis, vasodilation and increased vascular permeability, triggers mast cell degranulation,
chemotaxis, and opsonization.
Question 2
Prostacyclin
Correct Answer
Vasodilation, platelet aggregation (most effective one)
Question 3
Monocytopenia- definition and causes
Correct Answer
Decreased # of monocytes
From steroid use of HIV infection
Page 1 of 34
,Question 4
COX1
Correct Answer
Prostaglandin of arachidonic pathway. Provides gastroprotection, platelet aggregation, fluid/electrolyte balance
Question 5
CM of Hodgkin's Lymphoma
Correct Answer
Large painless lump/mass- usually on neck, eosinophilia, fever, weight loss, night sweats, pruritus, adenopathy,
thrombocytosis, leukocytosis, mediastinal or abdominal mass
Question 6
Arachidonic pathway purpose
Correct Answer
Synthesis of prostaglandins
Question 7
4th generation immunoassay
Correct Answer
"gold standard"
can test 10 days post exposure
can result negative, positive with HIV antibody, or positive without HIV antibody
Page 2 of 34
,Question 8
Effects of genetic mutation of CCR5 cell receptor
Correct Answer
Some people of European descent carry the CCR5 delta32 mutation. The mutation makes a person functionally resistant
to the HIV virus, and might be a cure for those individuals
Question 9
Prostaglandins
Correct Answer
Released when mast cells degranulate, are produced by the arachidonic pathway. Cause vasodilation, platelet
aggregation at site of injury, pain, and fever.
Question 10
discuss hemophilia A
Correct Answer
affects 1 in 5-10K males
sex linked recessive disease, deficient in factor VIII
normal platelets and PT, prolonged PTT, decreased factor VIII
CM: knee, elbow, and ankle bleeds, GI bleeds
Page 3 of 34
, Question 11
Alloimmunity and example of hypersensitivity
Correct Answer
When an individuals immune system reacts against antigens on the tissues of other members of the same species
Blood transfusions- causes clumping and lysis of RBC- fever, nausea, chills, low back pain, dark urine, hives, itching, SOB
Rh incompatibility- hemolytic disease of newborn with jaundice, give Rhogam within 72 hours of birth (Rh- mother with
Rh+ child)
Question 12
Discuss some clinical implications of solid organ transplant rejection
Correct Answer
rejection is an immune response, mostly T-cell mediated. Slow process, Type 4 hypersensitivity
Patients are highly susceptible to infections r/t use of immunosuppressants
Question 13
COX2
Correct Answer
Prostaglandin of arachidonic pathway. Responsible for pain, fever, renal protection, tissue repair, reproduction
development.
Page 4 of 34
