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FIRST AID USMLE STEP 2 CS MINI
CASES 2026 QUESTIONS AND
ANSWERS | A+ GRADED | WITH
EXPERT SOLUTIONS
Presentation:
26 yo M presents after falling and losing consciousness at work.
He had rhythmic movements of the limbs, bit his tongue, and lost
control of his bladder. He was subsequently confused after
regaining consciousness (as witnessed by his colleagues) -
correct answer-Differential:
Generalized tonic-clonic seizure
Convulsive syncope
Substance abuse/overdose
Malingering
Hypoglycemia
Workup:
CBC
Electrolytes, glucose
Urine toxicology
EEG
MRI—brain
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CT—head
LP—CSF analysis
ECG
Presentation:
34 yo F nurse presents with worsening cough of 6 weeks'
duration accompanied by weight loss, fatigue, night sweats, and
fever. She has a history of contact with tuberculosis patients at
work. - correct answer-Differential:
Tuberculosis
Pneumonia
Lung abscess
Vasculitis
Lymphoma
Metastatic cancer
HIV/AIDS
Sarcoidosis
Workup:
CBC
PPD/QuantiFERON Gold
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Presentation:
55 yo F c/o dizziness for the past day. She feels faint and has
severe diarrhea that started 2 days ago. She takes furosemide for
hypertension. - correct answer-Differential:
Orthostatic hypotension due to dehydration (diarrhea, diuretic
use)
Vestibular neuronitis
Labyrinthitis
Benign positional vertigo
Vertebrobasilar insufficiency
Workup:
Orthostatic vital signs
CBC
Electrolytes
Rectal exam, stool for occult blood
Stool leukocytes
Presentation:
65 yo M presents after falling and losing consciousness for a few
seconds. He had no warning before passing out but recently had
palpitations. His history includes a coronary artery bypass graft. -
correct answer-Differential:
Cardiac arrhythmia (causing syncope)
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Severe aortic stenosis
Syncope (other causes)
Seizure
Pulmonary embolism
Workup:
ECG
Holter monitoring
CBC
Electrolytes, glucose
Echocardiography
CT—head
Presentation:
1-month-old F is brought in because she has been spitting up her
milk for the last 10 days. The vomiting episodes have increased in
frequency and forcefulness. Emesis is nonbloody and nonbilious.
The episodes usually occur immediately after breastfeeding. She
has stopped gaining weight. - correct answer-Differential:
Pyloric stenosis
Partial duodenal atresia
GERD
Gastroenteritis
FIRST AID USMLE STEP 2 CS MINI
CASES 2026 QUESTIONS AND
ANSWERS | A+ GRADED | WITH
EXPERT SOLUTIONS
Presentation:
26 yo M presents after falling and losing consciousness at work.
He had rhythmic movements of the limbs, bit his tongue, and lost
control of his bladder. He was subsequently confused after
regaining consciousness (as witnessed by his colleagues) -
correct answer-Differential:
Generalized tonic-clonic seizure
Convulsive syncope
Substance abuse/overdose
Malingering
Hypoglycemia
Workup:
CBC
Electrolytes, glucose
Urine toxicology
EEG
MRI—brain
, Page | 2
CT—head
LP—CSF analysis
ECG
Presentation:
34 yo F nurse presents with worsening cough of 6 weeks'
duration accompanied by weight loss, fatigue, night sweats, and
fever. She has a history of contact with tuberculosis patients at
work. - correct answer-Differential:
Tuberculosis
Pneumonia
Lung abscess
Vasculitis
Lymphoma
Metastatic cancer
HIV/AIDS
Sarcoidosis
Workup:
CBC
PPD/QuantiFERON Gold
, Page | 3
Presentation:
55 yo F c/o dizziness for the past day. She feels faint and has
severe diarrhea that started 2 days ago. She takes furosemide for
hypertension. - correct answer-Differential:
Orthostatic hypotension due to dehydration (diarrhea, diuretic
use)
Vestibular neuronitis
Labyrinthitis
Benign positional vertigo
Vertebrobasilar insufficiency
Workup:
Orthostatic vital signs
CBC
Electrolytes
Rectal exam, stool for occult blood
Stool leukocytes
Presentation:
65 yo M presents after falling and losing consciousness for a few
seconds. He had no warning before passing out but recently had
palpitations. His history includes a coronary artery bypass graft. -
correct answer-Differential:
Cardiac arrhythmia (causing syncope)
, Page | 4
Severe aortic stenosis
Syncope (other causes)
Seizure
Pulmonary embolism
Workup:
ECG
Holter monitoring
CBC
Electrolytes, glucose
Echocardiography
CT—head
Presentation:
1-month-old F is brought in because she has been spitting up her
milk for the last 10 days. The vomiting episodes have increased in
frequency and forcefulness. Emesis is nonbloody and nonbilious.
The episodes usually occur immediately after breastfeeding. She
has stopped gaining weight. - correct answer-Differential:
Pyloric stenosis
Partial duodenal atresia
GERD
Gastroenteritis
