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WGU D236 PATHOPHYSIOLOGY MIDTERM DETAILED EXAM 2026

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WGU D236 PATHOPHYSIOLOGY MIDTERM DETAILED EXAM 2026 What happens to the various anion levels in the bloodstream during diabetic ketoacidosis? - -The anion gap level increases, whereas the HCO3- level decreases. How do the kidneys compensate for alkalosis! - -By retaining more H+ and excreting more HCO3- What is one cause of edema? - -Diminished osmotic force created by low numbers of solutes in the bloodstream. What are two causes of metabolic acidosis due to increased noncarbonic acids? 2 answers. - -Diabetic ketoacidosis Lactic acidosis A health informatics professional is conducting a documentation review of records at the request of the Infection Control Department. The professional is tasked with flagging records of patients with diseases spread by respiratory secretions. What are two diseases that this HIM professional should flag? 2 answers. - -Varicella Influenza What should a healthcare provider recognize as part of a patient's adaptive immune response to an influenza virus? - -Generation of immunoglobulin M (IgM) Which apparent electrolyte imbalance may result from untreated acidosis? - Hyperkalemia What describes an antimicrobial peptide? - -A chain of amino acids produced by cells in response to pathogenic exposure. A patient with chronic hypertension developed enlargement of the left ventricle of the heart. What is the maladaptive cellular change that occurred in this patient? - -Pathological hypertrophy Two parents take genetic tests for sickle cell disease. Both parents are heterozygous. What are all the possible outcomes for their children? - -Heterozygous, homozygous normal, or homozygous sickle A six month old baby is diagnosed with Tay Sachs disease. WGU D236 WGU D236 Which developmental disruptions are associated with this disorder? - -Lethargy, muscle flaccidity, motor coordination impairment, and increasing cognitive impairment. Which fracture type is it when there is more than one fracture line, and more than two bone fragments are shattered or crushed? - -Comminuted What are two characteristics of osteoarthritis as opposed to rheumatoid arthritis? 2 answers - -The pathophysiology includes joint swelling and osteophyte formation. The most commonly affected joints are the knee, hip, hand, and proximal interphalangeal and distal interphalangeal joints. A healthcare professional examines a patient with a slow growing, small, dome shaped bump on the nose. The lesion is shiny, translucent, and pearly in appearance. Which type of lesion should this healthcare professional be concerned about? - -Basal cell carcinoma The record of a 35 year old woman contains the following information: Presentation: Sudden, transient motor and sensory disturbances, impaired vision, muscle weakness, and balance problems. Diagnostic work up including neurological exam, CT, MRI, and CSF analysis. The patient's diagnosis is a chronic, autoimmune, progressive, and irreversible disease characterized by the destruction of the myelin sheath. Which condition does this patient have? - -Multiple sclerosis A patient presents with ringing in the ears, vomiting, and a severe headache after playing football and taking a hard tackle. A CT scan shows that blood had accumulated in the surrounding brain tissue. Which diagnosis is described? - -Cerebral contusion What is the pathogenesis of multiple sclerosis? - -Damage to the myelin of the peripheral nervous system. What are two characteristics of a transient ischemic attack? 2 answers - -Focal deficits resolve in less than 24 hours. Symptoms last for minutes to hours. What is a cerebrovascular accident marked by a blockage of blood flow due to a rupture in a cerebral vessel? - -Hemorrhagic stroke Which two risk factors are associated with hypertension? 2 answers - -Obesity and Diabetes Mellitus What are two predisposing factors to deep venous thromboembolism? 2 answers - -Hyper-coagulability Vascular damage WGU D236 WGU D236 What are two parts of the pathophysiology of DVT? 2 answers - -A thrombus forms at an area of inflammation. A thrombus develops in a lower extremity. A patient presents with racing of the heart, palpitations, and shortness of breath. The patient's heart rate was 130. Which diagnosis is indicated by this description? - -Atrial fibrillation What is a characteristic of aneurysms? - -Hypertension is a risk factor for aneurysm formation. What is a clot or undissolved mass that is carried through the circulatory vessels by blood or lymph flow? - -Embolus A patient's record shows chronic blood loss anemia. Which form of anemia does this indicate? - -Iron deficiency anemia Which is this type of anemia? Occurs when there are inadequate reserves of iron in the body. - -Iron deficiency anemia Which is this type of anemia? Occurs when there are inadequate stores of folic acid. - -Folic acid deficiency anemia Which is this type of anemia? Occurs when there are inadequate levels of B12. - -Pernicious anemia Which is this type of anemia? Occurs when there is insufficient or totally absent red blood cell production. - -Aplastic anemia Which disorder is characterized by the development of binucleate Reed Sternberg cells? - -Hodgkin's lymphoma What are two of the symptoms of SLE? 2 answers - -Fatigue and fever A patient is receiving treatment for Hodgkin disease. What is a possible complication of the treatment for Hodgkin disease? - -A weakened immune system WGU D236 WGU D236 Which two conditions are considered as inflammation of the upper respiratory tract? 2 answers - -Pharyngitis and croup What are two signs of a pneumothorax? 2 answers - -Dyspnea and intercostal muscle retractions. Which pathophysiological characteristic is associated with pneumonia? - -Exudates filling the air spaces of alveoli. What are two common causes of an obstruction in the large intestine? 2 answers - -A cancerous mass Benign polyps On physical examination, a patient is noted to have pallor, ascites, cachexia, and hepatomegaly. On history, the patient complained of alternating diarrhea and constipation and blood in the stool. A barium X-ray was done, followed by a biopsy that confirmed the diagnosis. Based on this information, which diagnosis is indicated? - -Colon cancer Which two symptoms are associated with Crohn's disease? 2 answers - -Chronic diarrhea Abdominal pain A 49 year old patient with diabetes complained of right upper quadrant (RUQ) abdominal pain that appears to radiate to her back. The patient also complains of

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WGU D236




WGU D236 PATHOPHYSIOLOGY
MIDTERM DETAILED EXAM 2026
What happens to the various anion levels in the bloodstream during diabetic
ketoacidosis? - -The anion gap level increases, whereas the HCO3- level decreases.

How do the kidneys compensate for alkalosis! - -By retaining more H+ and excreting
more HCO3-

What is one cause of edema? - -Diminished osmotic force created by low numbers of
solutes in the bloodstream.

What are two causes of metabolic acidosis due to increased noncarbonic acids?
2 answers. - -Diabetic ketoacidosis
Lactic acidosis

A health informatics professional is conducting a documentation review of records at the
request of the Infection Control Department. The professional is tasked with flagging
records of patients with diseases spread by respiratory secretions.
What are two diseases that this HIM professional should flag? 2 answers. - -Varicella
Influenza

What should a healthcare provider recognize as part of a patient's adaptive immune
response to an influenza virus? - -Generation of immunoglobulin M (IgM)

Which apparent electrolyte imbalance may result from untreated acidosis? - -
Hyperkalemia

What describes an antimicrobial peptide? - -A chain of amino acids produced by cells in
response to pathogenic exposure.

A patient with chronic hypertension developed enlargement of the left ventricle of the
heart.
What is the maladaptive cellular change that occurred in this patient? - -Pathological
hypertrophy

Two parents take genetic tests for sickle cell disease. Both parents are heterozygous.
What are all the possible outcomes for their children? - -Heterozygous, homozygous
normal, or homozygous sickle

A six month old baby is diagnosed with Tay Sachs disease.

WGU D236

, WGU D236


Which developmental disruptions are associated with this disorder? - -Lethargy, muscle
flaccidity, motor coordination impairment, and increasing cognitive impairment.

Which fracture type is it when there is more than one fracture line, and more than two
bone fragments are shattered or crushed? - -Comminuted

What are two characteristics of osteoarthritis as opposed to rheumatoid arthritis?
2 answers - -The pathophysiology includes joint swelling and osteophyte formation.

The most commonly affected joints are the knee, hip, hand, and proximal
interphalangeal and distal interphalangeal joints.

A healthcare professional examines a patient with a slow growing, small, dome shaped
bump on the nose. The lesion is shiny, translucent, and pearly in appearance.
Which type of lesion should this healthcare professional be concerned about? - -Basal
cell carcinoma

The record of a 35 year old woman contains the following information:
Presentation: Sudden, transient motor and sensory disturbances, impaired vision,
muscle weakness, and balance problems.
Diagnostic work up including neurological exam, CT, MRI, and CSF analysis.
The patient's diagnosis is a chronic, autoimmune, progressive, and irreversible disease
characterized by the destruction of the myelin sheath.
Which condition does this patient have? - -Multiple sclerosis

A patient presents with ringing in the ears, vomiting, and a severe headache after
playing football and taking a hard tackle. A CT scan shows that blood had accumulated
in the surrounding brain tissue.
Which diagnosis is described? - -Cerebral contusion

What is the pathogenesis of multiple sclerosis? - -Damage to the myelin of the
peripheral nervous system.

What are two characteristics of a transient ischemic attack?
2 answers - -Focal deficits resolve in less than 24 hours.
Symptoms last for minutes to hours.

What is a cerebrovascular accident marked by a blockage of blood flow due to a rupture
in a cerebral vessel? - -Hemorrhagic stroke

Which two risk factors are associated with hypertension?
2 answers - -Obesity and Diabetes Mellitus

What are two predisposing factors to deep venous thromboembolism?
2 answers - -Hyper-coagulability
Vascular damage

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