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what 3 labs are used for diagnosing thyroid dx
TSH
Free T4
Total 3
what is the time frame for rechecking labs after starting synthroid
6-8 weeks after initiation or dose adjustment
signs and symptoms of hypothyroidism
Fatigue, weight gain, cold intolerance, dry skin, hair loss, constipation.
signs sand symptoms of hyperthyroidism
Weight loss
heat intolerance
anxiety
tremors
palpitations
increased appetite.
what medication treats thyroid storm
beta blockers
anti thyroid drugs(methimazole & PTU)
corticosteroids
,fluids
what is the first line treatment for hyperthyroidism
Methimazole
what happens when hypothyroidism is not treated during pregnancy
increased risk of miscarriage
pre term birth
developmental delays in child
what medication is used for treating hyperthyroid symptoms
beta blocks; propranolol for tachycardia & tremors
what food/drugs interact with synthroid
Calcium and iron supplements (reduce absorption).
Soy products (may interfere with absorption).
Antacids & ppi (containing aluminum or magnesium).
coumadin & cathecholmines
what thyroid medication can be taken in the 1st trimester of pregnancy
PTU (Propylthiouracil)
what thyroid treatment can be taken in 2nd & 3rd trimester of pregnancy
methimazole
what is a common side effect that warrants discontinuation of thyroid drug
agranulocytosis
what drug is used to treat hypothyroidism in infants & why is it important to
treat it
Synthroid- its important to treat early to prevent cognitive impairment
how is synthroid administered
, its an oral drug that is taken on an empty stomach 30-60 mins before breakfast
what are the adverse effects of synthroid
tachycardia, weight loss & anxiety
what lab is monitored when taking levothyroxine & how often
TSH level should be checked every 6-8 weeks when initiating or adjust dose and
then done annually
what is the MOA of Methimazole
Inhibits thyroid hormone synthesis by blocking the oxidation of iodine.
what does an increase in TSH indicate
thyroid production is LOW
what 3 test confirm diabetes diagnosis
A1C ≥ 6.5%
Fasting Plasma Glucose (FPG) ≥ 126 mg/dL
Oral Glucose Tolerance Test (OGTT) ≥ 200 mg/dLA1C
when should insulin be considered
when A1C is >10% or if there are symptoms of hyperglycemia
at what time interval should glucose labs be rechecked
every 3 months until goal is met and then every 6 months
how do you prevent diabetic nephropathy
Medications: ACE inhibitors or ARBs (renin-angiotensin system blockers).
Glycemic Control: Maintain HbA1c targets.
Blood Pressure Control: Goal of <140/90 mm Hg.
what is the action in insulin