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PHARM-105: WEEK 9 GASTROINTESTINAL PHARMACOLOGY – EXAM (NCLEX) QUESTIONS WITH A+ GRADED ANSWERS + NOTES & RATIONALES 2026

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Notes: Gastrointestinal pharmacology covers acid-controlling drugs, laxatives, antiemetics, and peptic ulcer medications. These drugs are essential for managing GERD, nausea, constipation, and peptic ulcer disease. Nursing considerations include monitoring for electrolyte imbalances, hydration status, side effects, and teaching proper administration timing and lifestyle modifications. Key Points:

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Uploaded on
January 26, 2026
Number of pages
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Written in
2025/2026
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PHARM-105: WEEK 9 GASTROINTESTINAL
PHARMACOLOGY – EXAM (NCLEX)
QUESTIONS WITH A+ GRADED ANSWERS +
NOTES & RATIONALES 2026




HOW TO USE THIS DOCUMENT
This document is a complete Week 9 pharmacology
learning unit for nursing students, focusing on GI
medications. It integrates teaching notes with NCLEX-
style questions and rationales for exam-focused learning.
Recommended Study Approach:
1. Read teaching notes first to understand drug classes,
mechanisms, and nursing considerations.
2. Use tables for rapid review.
3. Complete the 40 practice questions without
referring to notes.
4. Review the answer key and rationales.

, 5. Use the summary tables for pre-exam quick revision.
Learning Outcomes:
By completing this document, students will be able to:
 Identify major GI drug classes
 Recognize 1–2 key drugs per class and their
indications
 Apply nursing considerations and safety precautions
 Solve NCLEX-style GI pharmacology questions

1. Introduction & Learning Objectives
GI drugs are high-yield for NCLEX because they manage
common conditions like GERD, nausea, constipation, and
peptic ulcer disease. Understanding mechanisms, nursing
considerations, and adverse effects is crucial for safe
practice.
Objectives:
 Recognize key GI drugs
 Understand mechanisms and therapeutic effects
 Identify nursing considerations and patient teaching
points
 Solve NCLEX-style questions effectively

, 2. Acid-Controlling Drugs
Mechanism: Reduce gastric acid production or neutralize
stomach acid
Common Drugs:
 Antacids: Calcium carbonate, Aluminum hydroxide
 H2 Receptor Blockers: Ranitidine, Famotidine
 Proton Pump Inhibitors (PPIs): Omeprazole,
Pantoprazole
Effects: Relieve heartburn, GERD, and peptic ulcer
disease symptoms
Nursing Considerations:
 Monitor for constipation or diarrhea (especially with
antacids)
 Administer H2 blockers before meals or at bedtime
 PPIs are often given before meals; long-term use
may lead to osteoporosis or magnesium deficiency

3. Laxatives & Stool Softeners
Mechanism: Increase bowel motility or soften stool
Common Drugs:
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