NO. 507 MIDTERM EXAM 2

NR 507 MIDTERM EXAM 2

Examples of hypersensitivity type 1
ANSWER: allergic rhinitis, anaphylactic reaction

Type 1 hypersensitivity reactions are mediated by what
ANSWER: IgE

What cells are involved in hypersensitivity type 1
ANSWER: Mast cells

symptoms of hypersensitivity type 1
ANSWER: local: itching, immediate rash
systemic: wheezing

main treatment for anaphylaxis
ANSWER: epinephrine

Type 2 hypersensitivity is also known as what kind of reaction?
ANSWER: cytotoxic reaction, tissue specific

what cells are involved in type 2 hypersensitivity reaction?
ANSWER: Macrophages

what does type 2 hypersensitivity do to tissues?
ANSWER: can cause damage or alter function of specific tissues

Examples of hypersensitivity type 2
ANSWER: graves’ disease/ hyperthyroidism, blood incompatibility

what is the difference between type 2 and 3 hypersensitivity?
ANSWER: type 2 is organ specific; antibody binds to the antigen on the surface of
the cell
type 3 is NOT organ specific; binds outside of the cell surface and is released into
blood/ body fluids and then deposited into tissues

, examples of type 3 hypersensitivity
ANSWER: rheumatoid arthritis and lupus

autoimmune diseases can be...
ANSWER: genetic/familial

What is alloimmunity?
ANSWER: Immune reaction to tissues of another individual

Examples of alloimmunity
ANSWER: transplant rejection, transfusion reactions, Rh incompatibility

what is hypersensitivity type 4
ANSWER: Delayed response, Occurs 24
72 hours after exposure
does not involve antigen/antibody complexes

Hypersensitivity type 4 is mediated by what?
ANSWER: T cells!!!

example of hypersensitivity type 4
ANSWER: contact dermatitis
poison ivy
delayed response occurs in area of contact

organ rejection is made up of what hypersensitivity and why?
ANSWER: Type 2 and 4.
involves cytotoxicity (2)
T cells play a role in organ rejection (4)

atopic dermatitis is example of what
ANSWER: type 1 hypersensitivity