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1. Which action is a purpose of the inflammatory process: To prevent infection of the injured
tissue
2. How do surfactant proteins A through D provide innate resistance: Promote
phagocytosis
3. Which secretion is a first line of defense against pathogen invasion that
involves antibacterial and antifungal fatty acids, as well as lactic acid: Sebaceous
gland sebum
4. Which bacterium grows in the intestines after prolonged antibiotic therapy: -
Clostridium difficile
5. What causes the edema that occurs during the inflammatory process: Increased
capillary permeability
6. What process causes heat and redness to occur during the inflammatory
process: Vasodilation of blood vessels
7. Activation of the classical pathway begins with: Antigen-antibody complexes
8. What plasma protein system forms a fibrinous meshwork at an inflamed
site: Coagulation
9. Which component of the plasma protein system tags pathogenic microorgan-
isms for destruction by neutrophils and macrophages: Complement cascade
10. What is the vascular effect of histamine released from mast cells: Vasodilation
11. What is an outcome of the complement cascade: Lysis of bacterial cell membranes
12. The function of opsonization related to the complement cascade is to: Tag of
pathogenic microorganisms for destruction by neutrophils and macrophages
13. In the coagulation (clotting) cascade, the intrinsic and the extrinsic pathways
converge at which factor: X
14. Which chemical interacts among all plasma protein systems by degrading
blood clots, activating complement, and activating the Hageman factor: Plasmin
15. The chemotactic factor affects the inflammatory process by: Directing leukocytes to
the inflamed area
16. What affect does the process of histamine binding to the histamine-2(H2)
receptor have on inflammation: Inhibition
17. Frequently when H1 and H2 receptors are located on the same cells, they act
in what fashion: Antagonistically
, Patho NSG 5003 wk 2
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18. Some older adults have impaired inflammation and wound healing because
of which problem: Underlying chromic illness(es) exists
19. Which chemical mediator derived from mast cells retracts endothelial cells to
increase vascular permeability and to cause leukocyte adhesion to endothelial
cells: Platelet-activating factor
20. What is the inflammatory effect of nitric oxide (NO): Decreases mast cell function, and
decreases platelet aggregation
21. What is the correct sequence in phagocytosis: Recognition, engulfment, fusion, destruction
22. When considering white blood cell differentials, acute inflammatory reac-
tions are related to elevation of which leukocyte: Neutrophils
23. In the later stages of an inflammatory response, which phagocytic cell is
predominant: Monocytes
24. In regulating vascular mediators release from mast cells, the role of
eosinophils is to release: Histaminase, which limits the effects of histamine during acute inflammation
25. What is the role of a natural killer (NK) cells: Elimination of malignant cells
26. Which cytokine is produced and released from virally infected host cells: IFN-a
27. IFN-a is secreted from which cells: Macrophages
28. Which manifestation of inflammation is systemic: Fever and leukocytosis
29. The acute inflammatory response is characterized by fever that is produced
by the hypothalamus being affected by: Endogenous pyrogens
30. What occurs during the process of repair after tissue damage: Nonfuctioning scar
tissue replaces destroyed tissue
31. The role of fibroblasts during the reconstructive phase of wound healing is
to: Synthesize and secrete collagen and the connective tissue proteins
32. A keloid is the result of which dysfunctional wound healing response: collagen
matrix assembly
33. Which solution is best to use when cleaning a wound that is healing by
epithelialization: Normal saline
34. Many neonates have a transient depressed inflammatory response as a
result of which condition: Complement and chemotaxis are deficient
35. During phagocytosis, what is occurring during the step refereed to as op-
sonization: Phagocytes recognize and adhere to the bacteria