Medical-Surgical Nursing MCQs Study Guide | Clinical Judgment & Exam Review

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




High-Yield Nursing MCQs
Harrison’s Principles of Internal Medicine, 22nd ed. (Vols. 1–2)


1.
Which principle best distinguishes evidence-based medicine as
described in Harrison’s?
A. Reliance on expert opinion
B. Integration of best research evidence with clinical expertise
and patient values
C. Exclusive use of randomized controlled trials
D. Standardized care without patient input
Correct Answer: B
Rationale: Evidence-based medicine integrates scientific
evidence, clinician judgment, and patient preferences to
optimize care decisions.

,Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1 The Practice of Medicine


2.
Which factor is most strongly associated with sustained health
promotion behaviors?
A. Genetic predisposition
B. Access to technology
C. Social and environmental determinants
D. Acute illness experience
Correct Answer: C
Rationale: Social, economic, and environmental conditions
strongly influence health behaviors and long-term outcomes.
Citation: Harrison’s, 22nd ed., Ch. 2 Promoting Good Health


3.
A key contributor to vaccine hesitancy identified in Harrison’s is:
A. Vaccine supply shortages
B. Distrust in health systems and misinformation
C. Inadequate immune response
D. Increased adverse reactions
Correct Answer: B
Rationale: Misinformation and institutional distrust are major
drivers of vaccine opposition.

, Citation: Harrison’s, 22nd ed., Ch. 3 Vaccine Opposition and
Hesitancy


4.
Shared clinical decision-making is MOST appropriate when:
A. Evidence strongly favors one option
B. Patient preferences significantly affect outcomes
C. Emergency care is required
D. Diagnosis is uncertain
Correct Answer: B
Rationale: Shared decision-making is essential when multiple
reasonable options exist and patient values influence care
choices.
Citation: Harrison’s, 22nd ed., Ch. 4 Decision-Making in Clinical
Medicine


5.
Precision medicine primarily seeks to:
A. Replace population-based guidelines
B. Use genetic, environmental, and lifestyle data to individualize
care
C. Eliminate preventive screening
D. Focus solely on rare diseases