QIHC STUDY GUIDE – 7 2026
QUESTIONS AND ANSWERS| ACE
YOUR GRADES.
Which of the following is a chromogen used in peroxidase
histochemistry that generates a product that is soluble in alcohol
or xylene but not in water? - correct answer -9-
aminoethylcarbazole AEC
The best positive control tissue for IHC is one that is: - correct
answer -processed identically to patient tissue
A single normal human cell with a diploid, DNA index of 1.0
reflects the DNA contained in how many chromosomes? - correct
answer -46 chromosomes
An immunoglobulin molecule can be divided into two fragments
known as the antigen-binding fragment (Fab) and the
crystalizable fragment (Fc). The function of the crystalizable
fragment is to: - correct answer -be involved in biologic functions
other than antigen binding
1 | Page
, The antibody class most frequently demonstrated in
immunofluorescent and immunoenzyme staining is: - correct
answer -IgG
In reference to antibodies, the terms light and heavy chains refer
to the: - correct answer -molecular weight of the polypeptide
chains
The ability of an antibody to recognize and bind with a specific
protein antigen is due to its: - correct answer -3 D structure
Antibody diversity is due to different amino acid sequences of the:
- correct answer -variable regions in both the light and heavy
chains
Which of the following cells is responsible for immunoglobulin
production? - correct answer -plasma cell
A cell antigen that can be demonstrated by immunofluorescent
staining of fresh-frozen tissues is not visible by
2 | Page
QUESTIONS AND ANSWERS| ACE
YOUR GRADES.
Which of the following is a chromogen used in peroxidase
histochemistry that generates a product that is soluble in alcohol
or xylene but not in water? - correct answer -9-
aminoethylcarbazole AEC
The best positive control tissue for IHC is one that is: - correct
answer -processed identically to patient tissue
A single normal human cell with a diploid, DNA index of 1.0
reflects the DNA contained in how many chromosomes? - correct
answer -46 chromosomes
An immunoglobulin molecule can be divided into two fragments
known as the antigen-binding fragment (Fab) and the
crystalizable fragment (Fc). The function of the crystalizable
fragment is to: - correct answer -be involved in biologic functions
other than antigen binding
1 | Page
, The antibody class most frequently demonstrated in
immunofluorescent and immunoenzyme staining is: - correct
answer -IgG
In reference to antibodies, the terms light and heavy chains refer
to the: - correct answer -molecular weight of the polypeptide
chains
The ability of an antibody to recognize and bind with a specific
protein antigen is due to its: - correct answer -3 D structure
Antibody diversity is due to different amino acid sequences of the:
- correct answer -variable regions in both the light and heavy
chains
Which of the following cells is responsible for immunoglobulin
production? - correct answer -plasma cell
A cell antigen that can be demonstrated by immunofluorescent
staining of fresh-frozen tissues is not visible by
2 | Page
