HESI A2 ADMISSION ASSESSMENT PRACTICE EXAM
2026/2027 Complete Test | Anatomy, Biology, Chemistry,
Grammar, Reading, Math| Actual Questions & Verified Answers
| All Subject Areas | Pass Guarantee
SECTION 1: Anatomy & Physiology (Questions 1-40)
1. Which type of tissue is responsible for covering body surfaces and lining body
cavities?
A) Connective tissue
B) Muscle tissue
C) Epithelial tissue
D) Nervous tissue
Correct Answer: C
Rationale: Epithelial tissue forms protective barriers and lines surfaces, including the
skin, blood vessels, and hollow organs. Connective tissue supports and connects
structures, muscle tissue contracts, and nervous tissue transmits signals.
2. In which body cavity would you find the lungs?
A) Abdominal cavity
,B) Pelvic cavity
C) Thoracic cavity
D) Cranial cavity
Correct Answer: C
Rationale: The thoracic cavity contains the lungs and heart, separated from the
abdominal cavity by the diaphragm. The abdominal cavity holds digestive organs, the
pelvic cavity contains reproductive organs, and the cranial cavity houses the brain.
3. Which directional term means "closer to the midline of the body"?
A) Distal
B) Medial
C) Lateral
D) Proximal
Correct Answer: B
Rationale: Medial means toward the midline, while lateral means away from the midline.
Proximal means closer to the point of attachment or trunk, and distal means farther
away. These terms are essential for describing anatomical locations.
4. What is the primary function of red blood cells?
A) To fight infection
B) To carry oxygen
,C) To form blood clots
D) To regulate blood pressure
Correct Answer: B
Rationale: Red blood cells contain hemoglobin, which binds and transports oxygen from
the lungs to tissues. White blood cells fight infection, platelets form clots, and blood
pressure is regulated by vessels and the heart.
5. Which of the following structures is NOT part of the upper respiratory tract?
A) Pharynx
B) Larynx
C) Trachea
D) Nose
Correct Answer: C
Rationale: The upper respiratory tract includes the nose, nasal cavity, pharynx, and
larynx. The trachea (windpipe) marks the beginning of the lower respiratory tract, which
also includes bronchi and lungs.
6. Which chamber of the heart pumps oxygenated blood to the body?
A) Right atrium
B) Right ventricle
C) Left atrium
, D) Left ventricle
Correct Answer: D
Rationale: The left ventricle generates the high pressure needed to pump oxygenated
blood through the systemic circulation to the entire body. The right ventricle pumps
deoxygenated blood to the lungs, while the atria receive blood returning to the heart.
7. Which hormone lowers blood glucose levels?
A) Glucagon
B) Cortisol
C) Insulin
D) Epinephrine
Correct Answer: C
Rationale: Insulin, produced by pancreatic beta cells, facilitates glucose uptake into
cells, lowering blood glucose. Glucagon raises blood glucose by promoting glycogen
breakdown. Cortisol and epinephrine increase glucose availability during stress.
8. Where does gas exchange occur in the lungs?
A) Bronchi
B) Bronchioles
C) Alveoli
D) Trachea
2026/2027 Complete Test | Anatomy, Biology, Chemistry,
Grammar, Reading, Math| Actual Questions & Verified Answers
| All Subject Areas | Pass Guarantee
SECTION 1: Anatomy & Physiology (Questions 1-40)
1. Which type of tissue is responsible for covering body surfaces and lining body
cavities?
A) Connective tissue
B) Muscle tissue
C) Epithelial tissue
D) Nervous tissue
Correct Answer: C
Rationale: Epithelial tissue forms protective barriers and lines surfaces, including the
skin, blood vessels, and hollow organs. Connective tissue supports and connects
structures, muscle tissue contracts, and nervous tissue transmits signals.
2. In which body cavity would you find the lungs?
A) Abdominal cavity
,B) Pelvic cavity
C) Thoracic cavity
D) Cranial cavity
Correct Answer: C
Rationale: The thoracic cavity contains the lungs and heart, separated from the
abdominal cavity by the diaphragm. The abdominal cavity holds digestive organs, the
pelvic cavity contains reproductive organs, and the cranial cavity houses the brain.
3. Which directional term means "closer to the midline of the body"?
A) Distal
B) Medial
C) Lateral
D) Proximal
Correct Answer: B
Rationale: Medial means toward the midline, while lateral means away from the midline.
Proximal means closer to the point of attachment or trunk, and distal means farther
away. These terms are essential for describing anatomical locations.
4. What is the primary function of red blood cells?
A) To fight infection
B) To carry oxygen
,C) To form blood clots
D) To regulate blood pressure
Correct Answer: B
Rationale: Red blood cells contain hemoglobin, which binds and transports oxygen from
the lungs to tissues. White blood cells fight infection, platelets form clots, and blood
pressure is regulated by vessels and the heart.
5. Which of the following structures is NOT part of the upper respiratory tract?
A) Pharynx
B) Larynx
C) Trachea
D) Nose
Correct Answer: C
Rationale: The upper respiratory tract includes the nose, nasal cavity, pharynx, and
larynx. The trachea (windpipe) marks the beginning of the lower respiratory tract, which
also includes bronchi and lungs.
6. Which chamber of the heart pumps oxygenated blood to the body?
A) Right atrium
B) Right ventricle
C) Left atrium
, D) Left ventricle
Correct Answer: D
Rationale: The left ventricle generates the high pressure needed to pump oxygenated
blood through the systemic circulation to the entire body. The right ventricle pumps
deoxygenated blood to the lungs, while the atria receive blood returning to the heart.
7. Which hormone lowers blood glucose levels?
A) Glucagon
B) Cortisol
C) Insulin
D) Epinephrine
Correct Answer: C
Rationale: Insulin, produced by pancreatic beta cells, facilitates glucose uptake into
cells, lowering blood glucose. Glucagon raises blood glucose by promoting glycogen
breakdown. Cortisol and epinephrine increase glucose availability during stress.
8. Where does gas exchange occur in the lungs?
A) Bronchi
B) Bronchioles
C) Alveoli
D) Trachea