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NURS 5461 EXAM 1 QUESTIONS WITH CORRECT ANSWERS LATEST UPDATE 2026

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NURS 5461 EXAM 1 QUESTIONS WITH CORRECT ANSWERS LATEST UPDATE 2026 Microcytic anemia - Answers iron deficiency, usually due to malabsorption / occult blood loss, or lead poisoning. MCV <80 Normocytic anemia - Answers due to hemorrhage or chronic disease. Aplastic anemia. MVC 80-92 macrocytic anemia - Answers due to folate or vitamin B12(cobalamin) deficiency (megaloblastic anemia) / pernicious anemia. /liver diseases serum ferritin - Answers Tests for iron stores. As serum ferritin falls, TIBC rises, and serum iron levels will eventually fall. Anemia of chronic disease - Answers NORMOcytic anemia with ↓ serum iron, ↓ TIBC, and normal iron stores. Treat with epoetin and give an iron supplement Schistocytes - Answers Associated with hemolytic uremia syndrome pernicious anemia - Answers Macrocytic anemia caused by vitamin B12 deficiency. B12 is essential to maturation of erythrocytes - low levels will cause the RBC to expand. PPIs and histamine2 blockers can cause this. Increased homocysteine & methylmalonic acid level indicates ? - Answers B12 deficiency increased homocysteine levels - Answers Folate deficiency Sperocytes - Answers Appear as spheres, lack central pallor, smaller diameter, indicate immune-mediated process - can be seen after blood transfusion aplastic anemia - Answers a normocytic anemia characterized by the failure of bone marrow to produce red blood cells Low ferritin - Answers iron deficiency anemia Transferrin - Answers transports iron TIBC (total iron binding capacity) - Answers Available transferrin that is left unbound (Represents the "empty seats on a train"). When iron is low, TIBC will be high. When iron is high, TIBC will be low MCHC (mean corpuscular hemoglobin concentration) - Answers 32 - 36 g/dL Concentration of hemoglobin per RBC Alzheimer's disease - Answers Gradual onset with early memory impairment. Most common form of dementia. Cholinesterase inhibitors for early treatment. Lewy body dementia - Answers usually a rapidly progressive form of dementia seen with Parkinson syndrome. - VISUAL HALLUCINATION ARE SEEN.

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NURS 5461 EXAM 1 QUESTIONS WITH CORRECT ANSWERS LATEST UPDATE 2026



Microcytic anemia - Answers iron deficiency, usually due to malabsorption / occult blood loss, or
lead poisoning. MCV <80

Normocytic anemia - Answers due to hemorrhage or chronic disease. Aplastic anemia. MVC 80-
92

macrocytic anemia - Answers due to folate or vitamin B12(cobalamin) deficiency (megaloblastic
anemia) / pernicious anemia. /liver diseases

serum ferritin - Answers Tests for iron stores. As serum ferritin falls, TIBC rises, and serum iron
levels will eventually fall.

Anemia of chronic disease - Answers NORMOcytic anemia with ↓ serum iron, ↓ TIBC, and
normal iron stores. Treat with epoetin and give an iron supplement

Schistocytes - Answers Associated with hemolytic uremia syndrome

pernicious anemia - Answers Macrocytic anemia caused by vitamin B12 deficiency. B12 is
essential to maturation of erythrocytes - low levels will cause the RBC to expand. PPIs and
histamine2 blockers can cause this.

Increased homocysteine & methylmalonic acid level indicates ? - Answers B12 deficiency

increased homocysteine levels - Answers Folate deficiency

Sperocytes - Answers Appear as spheres, lack central pallor, smaller diameter, indicate immune-
mediated process - can be seen after blood transfusion

aplastic anemia - Answers a normocytic anemia characterized by the failure of bone marrow to
produce red blood cells

Low ferritin - Answers iron deficiency anemia

Transferrin - Answers transports iron

TIBC (total iron binding capacity) - Answers Available transferrin that is left unbound
(Represents the "empty seats on a train"). When iron is low, TIBC will be high. When iron is high,
TIBC will be low

MCHC (mean corpuscular hemoglobin concentration) - Answers 32 - 36 g/dL



Concentration of hemoglobin per RBC

, Alzheimer's disease - Answers Gradual onset with early memory impairment. Most common
form of dementia. Cholinesterase inhibitors for early treatment.

Lewy body dementia - Answers usually a rapidly progressive form of dementia seen with
Parkinson syndrome. - VISUAL HALLUCINATION ARE SEEN.

frontal lobe dementia - Answers Seen before age 60 w personality impairments. PDG-PET Scan
testing. - decreased glucose uptake by the brain in frontal and temporal lobe

PDG-PET SCAN - Answers Measure brain metabolism of glucose. decreaesd uptake by temporal
and parital lobe in Alzheimer's

SSRIs - Answers Fluoxetine, paroxetine, sertraline, citalopram.

Cholinesterase inhibitors - Answers Donepezil

Rivastigmine

Galantamine

Cholinesterase inhibitors - Answers Treatment of alzheimers dementia and dementia w Lewy
body's - can reduce psychosis & behavior disturbances

delirium - Answers Acute onset confusion caused by cholinergic deficiency / Anticholinergic
overdose. HALDO TREATMENT OF CHOICE UNLESS PT HAS PARKINSONS OR DEMENTIA W LEWY
BODYS - USE QUETIAPINE

For Mania in dementia use - Answers Divalproex (depokote)

1st recommended treatment for depression - Answers Exercise

Bipolar depression treatment - Answers mood stabilizer - lamotrigine 1st

Fluoxetine (Prozac) - Answers SSRI - AVOID IN OLDER ADULTS - long half life and too energizing

What neurotransmitter is lost in Alzheimer's - Answers Acetylcholine

Diagnosis for levy body / parkinson dementia - Answers must include visual hallucinations and
or parkinsons signs

Memantine - Answers Used for sever Alzheimer's and in combination with a cholinesterase
inhibitor

Citalopram (Celexa) - Answers SSRI. Effective in treating agitation and psychosis - no more than
20mg due to prolonged QT .

Treatment for mania in dementia - Answers Divalproex Sodium (Depakot) - Keep an eye on the
liver

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