Harrison’s-Based Nursing MCQ Study Guide & Medical-Surgical Test Bank

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




The Practice of Medicine
Q1. A 68-year-old patient with multiple chronic conditions is
admitted for an acute exacerbation. Which nursing action best
reflects the practice-of-medicine principle of patient-centered
care?
A. Focus documentation only on the acute problem.
B. Implement standardized orders without discussion.
C. Assess the patient’s values and priorities for care and include
them in the plan.
D. Prioritize discharge planning after treatment is complete.
Answer: C
Rationale: Patient-centered practice requires eliciting patient
values and incorporating them into the care plan to guide
decisions and goals.
Citation: Harrison’s, 22nd ed., Chapter: The Practice of
Medicine.
Promoting Good Health
Q2. A nurse leading a community health program wants to

,prioritize interventions with the greatest population health
impact. Which strategy aligns best with primary prevention?
A. Increasing screening for early disease detection.
B. Promoting smoking cessation in teens.
C. Managing glycemic control in diagnosed diabetics.
D. Providing rehabilitation after stroke.
Answer: B
Rationale: Primary prevention prevents disease before it occurs
(e.g., smoking prevention); screening is secondary prevention,
disease management and rehab are tertiary.
Citation: Harrison’s, 22nd ed., Chapter: Promoting Good Health.
Vaccine Opposition and Hesitancy
Q3. A parent expresses vaccine hesitancy due to safety
concerns. Which nursing response is most effective to reduce
hesitancy?
A. Dismiss the concern and state vaccines are mandatory.
B. Provide empathetic listening, correct misinformation with
clear facts, and offer evidence-based resources.
C. Refuse to vaccinate until the parent consents.
D. Tell the parent vaccine refusal will lead to legal
consequences.
Answer: B
Rationale: Empathic communication, correcting
misinformation, and offering reliable resources are evidence-
based approaches to address hesitancy and promote
acceptance.

, Citation: Harrison’s, 22nd ed., Chapter: Vaccine Opposition and
Hesitancy.
Decision-Making in Clinical Medicine (1 of 2)
Q4. When choosing among diagnostic tests with varying
sensitivity and specificity in a low-prevalence population, which
principle should guide nursing communication about test
results?
A. Positive predictive value will be high.
B. Negative predictive value is less useful.
C. A positive result may have a higher chance of being a false
positive.
D. Test choice does not depend on prevalence.
Answer: C
Rationale: In low-prevalence settings positive predictive value
falls, increasing false positives; clinicians should explain this to
patients.
Citation: Harrison’s, 22nd ed., Chapter: Decision-Making in
Clinical Medicine.
Decision-Making in Clinical Medicine (2 of 2)
Q5. A nurse is part of a team using shared decision-making for a
treatment with uncertain benefit. Which action best supports
shared decision-making?
A. Provide only the clinician’s recommendation.
B. Present risks, benefits, and alternatives and elicit patient
preferences.
C. Make the decision for the patient to expedite care.