Genomics & Gene Therapy (BIO310) | 80+ Verified Q&As on DNA, Inheritance, PCR, Recombinant DNA, Gene Editing

This document includes over 80 expertly verified Q&As that cover essential terminology and principles from the Genomics and Gene Therapy course (BIO310). It is a comprehensive glossary and conceptual resource, focusing on the structure, function, expression, and manipulation of genetic material at both molecular and clinical levels. Topics range from the basic building blocks of DNA and RNA to complex concepts such as gene expression regulation, genotype vs. phenotype, and chromosome abnormalities (e.g., aneuploidy, nondisjunction, polyploidy). The document also addresses key molecular biology tools including PCR, gel electrophoresis, gene cloning, and DNA sequencing. It provides insights into genomic disorders, inheritance patterns (dominant, recessive, sex-linked), and therapeutic innovations such as in vivo and ex vivo gene therapy, transgenic organisms, and biotechnology applications. Students will also benefit from the inclusion of advanced terms like functional genomics, comparative genomics, proteomics, and bioinformatics, linking gene therapy to systems biology and personalized medicine. This resource is ideal for: Undergraduate students in genetics, biotechnology, and molecular biology Pre-med and life science majors preparing for MCAT, end-of-semester, or midterm exams Students taking applied genomics or clinical genetics courses Graduate students and research assistants in genomics and therapeutic development Pharmacy and biomedical engineering students learning gene-based therapies This is a thorough, concept-rich study aid that bridges definitions with scientific context and exam relevance. Keywords: genome, exome, genomics, gene expression, gene therapy, DNA replication, PCR, codon, genotype, phenotype, dominant inheritance, aneuploidy, polygenic traits, recombinant DNA, gel electrophoresis, bioinformatics, proteomics, in vivo therapy, ex vivo therapy, transgenic organisms, chromosome disorders