Medical-Surgical Nursing MCQ Study Guide & Practice Test Bank

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




1. The Practice of Medicine
1. Which principle best distinguishes modern internal medicine
practice as described in Harrison’s?
A. Reliance on technological diagnostics over clinical judgment
B. Integration of scientific evidence with patient-centered care
C. Disease-focused management independent of social context
D. Algorithm-driven decision-making without clinician discretion
Correct Answer: B
Rationale: Harrison’s emphasizes integrating biomedical science
with individualized, patient-centered decision-making.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1 – The Practice of Medicine


2. Promoting Good Health

,2. Which nursing intervention most directly aligns with
Harrison’s framework for health promotion?
A. Treating disease after symptom onset
B. Emphasizing lifestyle modification to reduce disease risk
C. Prioritizing pharmacologic prevention
D. Screening only high-risk populations
Correct Answer: B
Rationale: Health promotion focuses on behavioral and lifestyle
interventions to prevent disease before onset.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 2 – Promoting Good Health


3. Vaccine Opposition and Hesitancy
3. A nurse addressing vaccine hesitancy should prioritize which
approach according to Harrison’s?
A. Providing authoritative instructions
B. Dismissing misinformation directly
C. Engaging in respectful, trust-based communication
D. Referring immediately to public health authorities
Correct Answer: C
Rationale: Harrison’s stresses empathetic dialogue and trust-
building to address vaccine hesitancy effectively.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 3 – Vaccine Opposition and Hesitancy

, 4. Decision-Making in Clinical Medicine
4. Clinical decision-making errors most commonly result from:
A. Lack of diagnostic testing
B. Cognitive biases and heuristics
C. Inadequate patient compliance
D. Time constraints alone
Correct Answer: B
Rationale: Harrison’s identifies cognitive biases as a major
contributor to diagnostic and management errors.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 4 – Decision-Making in Clinical Medicine


5. Precision Medicine and Clinical Care
5. Precision medicine primarily aims to:
A. Replace clinical assessment
B. Use population averages to guide care
C. Tailor care based on individual variability
D. Reduce clinician involvement
Correct Answer: C
Rationale: Precision medicine individualizes care using genetic,
environmental, and lifestyle factors.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 5 – Precision Medicine and Clinical Care