Medical-Surgical Nursing MCQ Study Guide and Practice Test Bank

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




High-Yield MCQs (Chapters 1–13)
Total: 20 Questions


1. (Ch. 1 – The Practice of Medicine)
A nurse caring for a patient with multiple chronic conditions
notes conflicting treatment goals between specialties. What
principle of modern medical practice should guide nursing
advocacy in this situation?
A. Evidence-based standardization
B. Patient-centered care coordination
C. Cost-effectiveness analysis
D. Disease-focused management
Correct Answer: B
Rationale: Harrison emphasizes patient-centered, coordinated
care as central to modern practice, particularly for complex,
multi-morbidity patients. Nurses play a key role in aligning care

,plans with patient goals.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1 – The Practice of Medicine


2. (Ch. 2 – Promoting Good Health)
Which nursing intervention best reflects a population-based
approach to health promotion?
A. Teaching medication administration techniques
B. Screening for hypertension in community clinics
C. Administering IV fluids for dehydration
D. Monitoring inpatient vital signs
Correct Answer: B
Rationale: Harrison defines health promotion as focusing on
prevention and population-level risk reduction, such as
community screening programs.
Citation: Harrison, 22nd ed., Ch. 2 – Promoting Good Health


3. (Ch. 3 – Vaccine Opposition and Hesitancy)
A parent expresses fear about vaccine safety. What is the
nurse’s most evidence-based response?
A. Provide clear risk-benefit education using credible sources
B. Dismiss the concern to prevent misinformation
C. Refer the parent immediately to legal policy
D. Avoid the discussion to maintain trust

, Correct Answer: A
Rationale: Harrison emphasizes respectful communication,
addressing concerns with transparent, evidence-based
information to build trust and improve vaccine acceptance.
Citation: Harrison, 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy


4. (Ch. 4 – Decision-Making in Clinical Medicine)
Which factor most strongly influences shared clinical decision-
making?
A. Physician preference
B. Institutional protocol
C. Patient values and goals
D. Cost of treatment
Correct Answer: C
Rationale: Harrison identifies patient values as central to shared
decision-making, especially when multiple reasonable clinical
options exist.
Citation: Harrison, 22nd ed., Ch. 4 – Decision-Making in Clinical
Medicine


5. (Ch. 5 – Precision Medicine and Clinical Care)
Which nursing role best supports precision medicine?