Medical-Surgical Nursing MCQ Study Guide & Practice Test Bank (Harrison’s-Based)

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




1. The Practice of Medicine
Which principle best defines evidence-based medical practice
as described in Harrison’s?
A. Reliance on expert opinion
B. Integration of clinical experience with best research evidence
C. Use of randomized trials only
D. Adherence to institutional protocols
Answer: B
Rationale: Evidence-based medicine integrates clinical
expertise, patient values, and the best available evidence.
Citation: Harrison’s 22nd ed., Ch. 1 – The Practice of Medicine


2. The Practice of Medicine
Which nursing action best supports patient-centered care?
A. Standardizing care regardless of preferences

,B. Prioritizing efficiency over communication
C. Incorporating patient values into care decisions
D. Limiting patient involvement
Answer: C
Rationale: Patient-centered care emphasizes shared decision-
making and respect for patient values.
Citation: Harrison’s 22nd ed., Ch. 1


3. Promoting Good Health
Which factor contributes MOST to preventable morbidity in
the U.S.?
A. Genetic disease
B. Infectious outbreaks
C. Behavioral risk factors
D. Environmental toxins
Answer: C
Rationale: Lifestyle behaviors such as smoking and poor diet
are major contributors to preventable disease.
Citation: Harrison’s 22nd ed., Ch. 2 – Promoting Good Health


4. Promoting Good Health
Which nursing intervention best aligns with primary
prevention?
A. Blood pressure control

, B. Smoking cessation counseling
C. Cancer screening
D. Rehabilitation therapy
Answer: B
Rationale: Primary prevention targets risk factors before
disease develops.
Citation: Harrison’s 22nd ed., Ch. 2


5. Vaccine Opposition and Hesitancy
Which approach is most effective in addressing vaccine
hesitancy?
A. Mandating vaccination
B. Providing factual, empathetic communication
C. Avoiding discussion
D. Using fear-based messaging
Answer: B
Rationale: Trust-based, respectful communication improves
vaccine acceptance.
Citation: Harrison’s 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy


6. Vaccine Opposition and Hesitancy
Which factor is commonly associated with vaccine refusal?
A. High health literacy